Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection (Q27681171)

protein monoubiquitination

GOA release 2020-03-11

1 reference

Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis

GOA release 2020-03-11

Jennifer Anne Miles

3

0 references

Helen Walden

series ordinal

4

object named as

Helen Walden

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author name string

Charlotte Hodson

series ordinal

1

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Andrew Purkiss

series ordinal

2

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publication date

4 February 2014

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published in

Structure

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volume

22

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issue

2

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page(s)

337-44

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

20 March 2017

1 reference

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Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

20 March 2017

1 reference

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Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system

20 March 2017

1 reference

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Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

E2 interaction and dimerization in the crystal structure of TRAF6

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

20 March 2017

1 reference

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Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

20 March 2017

1 reference

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Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

20 March 2017

1 reference

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Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

RING domain E3 ubiquitin ligases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Phasercrystallographic software

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

The finer things in X-ray diffraction data collection

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

A novel ubiquitin ligase is deficient in Fanconi anemia

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Positional cloning of a novel Fanconi anemia gene, FANCD2

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Building ubiquitin chains: E2 enzymes at work

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Ubiquitin: structures, functions, mechanisms

7 April 2017

1 reference

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A robust bulk-solvent correction and anisotropic scaling procedure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

24 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Human proteome-scale structural modeling of E2-E3 interactions exploiting interface motifs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

The family of ubiquitin-conjugating enzymes (E2s): deciding between life and death of proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

RF cloning: a restriction-free method for inserting target genes into plasmids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Fanconi's anemia and malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979106

Ubiquitin transfer from the E2 perspective: why is UbcH5 so promiscuous?

2 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24389026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure-based approaches to create new E2-E3 enzyme pairs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24389026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2013.12.004

1 reference

1 reference

1 reference

PubMed publication ID

24389026

1 reference