Membrane Topology and Function of Dengue Virus NS2A Protein (Q27676369)

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CongBao Kang

object named as

CongBao Kang

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Pei-Yong Shi

5

object named as

Pei-Yong Shi

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author name string

Zhiming Yuan

Solution structure of a human minimembrane protein Ost4, a subunit of the oligosaccharyltransferase complex

4

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publication date

April 2013

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published in

Journal of Virology

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volume

87

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page(s)

4609-22

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issue

8

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cites work

1 reference

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NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness

20 March 2017

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The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure

20 March 2017

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NS5 of dengue virus mediates STAT2 binding and degradation

20 March 2017

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Role of Nonstructural Protein NS2A in Flavivirus Assembly

20 March 2017

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Yellow Fever Virus NS3 Plays an Essential Role in Virus Assembly Independent of Its Known Enzymatic Functions

20 March 2017

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Structure and Function of Flavivirus NS5 Methyltransferase

20 March 2017

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West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5

20 March 2017

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A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice

20 March 2017

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Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of Flaviviruses

20 March 2017

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Inhibition of interferon signaling by dengue virus

20 March 2017

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An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

20 March 2017

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Mutations in the Yellow Fever Virus Nonstructural Protein NS2A Selectively Block Production of Infectious Particles

20 March 2017

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trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication

20 March 2017

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RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria

20 March 2017

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Evidence that flavivirus NS1-NS2A cleavage is mediated by a membrane-bound host protease in the endoplasmic reticulum

20 March 2017

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Cleavage of dengue virus NS1-NS2A requires an octapeptide sequence at the C terminus of NS1

20 March 2017

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Automated NMR structure calculation with CYANA

20 March 2017

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2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase

20 March 2017

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Composition and three-dimensional architecture of the dengue virus replication and assembly sites

20 March 2017

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A novel coding-region RNA element modulates infectious dengue virus particle production in both mammalian and mosquito cells and regulates viral replication in Aedes aegypti mosquitoes

7 April 2017

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Blocking double-stranded RNA-activated protein kinase PKR by Japanese encephalitis virus nonstructural protein 2A.

29 September 2017

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Inhibition of dengue virus by targeting viral NS4B protein

29 September 2017

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Solution NMR study of integral membrane proteins

29 September 2017

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Development and characterization of a stable luciferase dengue virus for high-throughput screening

29 September 2017

1 reference

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N-linked glycosylation of dengue virus NS1 protein modulates secretion, cell-surface expression, hexamer stability, and interactions with human complement

29 September 2017

1 reference

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Functional analysis of two cavities in flavivirus NS5 polymerase

29 September 2017

1 reference

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Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.

29 September 2017

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The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement

29 September 2017

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Subcellular localization and membrane topology of the Dengue virus type 2 Non-structural protein 4B.

29 September 2017

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Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase

29 September 2017

1 reference

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Identification of a major determinant of mouse neurovirulence of dengue virus type 2 using stably cloned genomic-length cDNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

Mutagenesis of the yellow fever virus NS2A/2B cleavage site: effects on proteolytic processing, viral replication, and evidence for alternative processing of the NS2A protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

Yellow fever virus proteins NS2A, NS2B, and NS4B: identification and partial N-terminal amino acid sequence analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

In vitro synthesis of West Nile virus proteins indicates that the amino-terminal segment of the NS3 protein contains the active centre of the protease which cleaves the viral polyprotein after multiple basic amino acids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

Methylation status of intracellular dengue type 2 40 S RNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

An evaluation of chemical shift index-based secondary structure determination in proteins: influence of random coil chemical shifts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

The fluorescence protease protection (FPP) assay to determine protein localization and membrane topology.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

Subcellular localization and some biochemical properties of the flavivirus Kunjin nonstructural proteins NS2A and NS4A.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624351

27 November 2018

Identifiers

DOI

10.1128/JVI.02424-12

1 reference

3960592

3960592

1 reference

1 reference

1 reference