Mechanism by which the lectin actinohivin blocks HIV infection of target cells (Q27657228)

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6 February 2020

title

Mechanism by which the lectin actinohivin blocks HIV infection of target cells (English)

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4

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Yukishige Ito

7

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6 February 2020

author name string

Haruo Tanaka

1

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6 February 2020

Harumi Chiba

2

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6 February 2020

Junji Inokoshi

3

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Takahiro Sugai

5

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Atsushi Takahashi

6

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6 February 2020

Masaru Tsunoda

8

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6 February 2020

Kaoru Suzuki

9

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6 February 2020

Akio Takénaka

10

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Takeshi Sekiguchi

11

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6 February 2020

Hideaki Umeyama

12

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Jun Hirabayashi

13

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Satoshi Omura

14

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language of work or name

English

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publication date

26 August 2009

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Proceedings of the National Academy of Sciences of the United States of America

6 February 2020

published in

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volume

106

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6 February 2020

page(s)

15633-15638

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6 February 2020

issue

37

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Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: structural basis for high-affinity carbohydrate-mediated binding to gp120

6 February 2020

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29 September 2017

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High-throughput analysis of lectin-oligosaccharide interactions by automated frontal affinity chromatography

29 September 2017

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Mutational pathways, resistance profile, and side effects of cyanovirin relative to human immunodeficiency virus type 1 strains with N-glycan deletions in their gp120 envelopes

29 September 2017

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Essential regions for antiviral activities of actinohivin, a sugar-binding anti-human immunodeficiency virus protein from an actinomycete

29 September 2017

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Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection

29 September 2017

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Actinohivin, a novel anti-human immunodeficiency virus protein from an actinomycete, inhibits viral entry to cells by binding high-mannose type sugar chains of gp120.

29 September 2017

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Longispora albida gen. nov., sp. nov., a novel genus of the family Micromonosporaceae

29 September 2017

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Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization

29 September 2017

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Site-specific discrimination by cyanovirin-N for alpha-linked trisaccharides comprising the three arms of Man(8) and Man(9).

29 September 2017

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Cell surface receptors, virus entry and tropism of primate lentiviruses

29 September 2017

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The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

29 September 2017

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The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

29 September 2017

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A simple screening system for anti-HIV drugs: syncytium formation assay using T-cell line tropic and macrophage tropic HIV env expressing cell lines--establishment and validation.

29 September 2017

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The potent anti-HIV protein cyanovirin-N contains two novel carbohydrate binding sites that selectively bind to Man(8) D1D3 and Man(9) with nanomolar affinity: implications for binding to the HIV envelope protein gp120.

29 September 2017

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Actinohivin, a novel anti-HIV protein from an actinomycete that inhibits syncytium formation: isolation, characterization, and biological activities

29 September 2017

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Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner

29 September 2017

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Selective interactions of the human immunodeficiency virus-inactivating protein cyanovirin-N with high-mannose oligosaccharides on gp120 and other glycoproteins.

29 September 2017

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The high degree of internal flexibility observed for an oligomannose oligosaccharide does not alter the overall topology of the molecule

29 September 2017

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29 September 2017

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29 September 2017

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Molecular cloning of actinohivin, a novel anti-HIV protein from an actinomycete, and its expression in Escherichia coli

29 September 2017

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2 June 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0907572106

Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

21 January 2018

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Safety concerns for the potential use of cyanovirin-N as a microbicidal anti-HIV agent

21 January 2018

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Frontal affinity chromatography as a tool for elucidation of sugar recognition properties of lectins

21 January 2018

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Targeting the glycans of gp120: a novel approach aimed at the Achilles heel of HIV

27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19717426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

AIDS research. Did Merck's failed HIV vaccine cause harm?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19717426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0907572106

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19717426%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

ADS bibcode

2009PNAS..10615633T

0 references

1 reference

2 references

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6 February 2020

2 references