MCM DNA helicase complex subunit MCM5 YLR274W (Q27553099)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P29496

DNA replication licensing factor Mcm5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P29496

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P29496

MCM N-terminal domain, protein family

1 reference

MCM OB domain, protein family

1 reference

MCM domain, protein family

1 reference

Mini-chromosome maintenance, conserved site, protein family

1 reference

Saccharomyces cerevisiae S288c

found in taxon

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

1 reference

9 May 2019

single-stranded DNA binding

1 reference

8 April 2019

Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

1 reference

9 May 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

1 reference

9 May 2019

DNA replication origin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

3 references

8 April 2019

8 April 2019

The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

8 April 2019

Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

single-stranded DNA helicase activity

1 reference

8 April 2019

The Mcm2-7 complex has in vitro helicase activity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

protein binding

7 references

9 May 2019

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Defining the budding yeast chromatin‐associated interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

A new MCM modification cycle regulates DNA replication initiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

DNA replication origin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

4 references

9 May 2019

9 May 2019

The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

3'-5' DNA helicase activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

DNA replication preinitiation complex

cell component

1 reference

9 May 2019

Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

replication fork protection complex

1 reference

9 May 2019

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

8 April 2019

8 April 2019

Subcellular localization of yeast CDC46 varies with the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

1 reference

9 May 2019

TAS

CMG complex

1 reference

9 May 2019

The architecture of a eukaryotic replisome.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

cytoplasm

1 reference

9 May 2019

Subcellular localization of yeast CDC46 varies with the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

9 May 2019

Subcellular localization of yeast CDC46 varies with the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

MCM complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

3 references

9 May 2019

9 May 2019

Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

biological process

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

1 reference

9 May 2019

pre-replicative complex assembly involved in nuclear cell cycle DNA replication

1 reference

8 April 2019

Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

double-strand break repair via break-induced replication

1 reference

8 April 2019

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

regulation of DNA-dependent DNA replication initiation

1 reference

9 May 2019

Cell cycle dependent topological changes of chromosomal replication origins in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

nuclear DNA replication

1 reference

9 May 2019

A group of interacting yeast DNA replication genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

DNA duplex unwinding

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

double-strand break repair via break-induced replication

DNA replication initiation

Subcellular localization of yeast CDC46 varies with the cell cycle

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29496

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference