Coiled-coil domain-containing protein MAD1 YGL086W (Q27551094)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40957

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

14 February 2019

Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

14 February 2019

The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

14 February 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

molecular function

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40957&geneProductId=UniProtKB:P40957

protein-containing complex binding

ND

IDA

1 reference

14 February 2019

The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

IDA

cell component

nuclear pore

IDA

mitotic spindle

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

kinetochore

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

nuclear envelope

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

mitotic DNA integrity checkpoint signaling

biological process

IGI

1 reference

14 February 2019

A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

negative regulation of protein import into nucleus during spindle assembly checkpoint

IGI

1 reference

14 February 2019

Mitosis-Specific Regulation of Nuclear Transport by the Spindle Assembly Checkpoint Protein Mad1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

1 reference

14 February 2019

IEA

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

1 reference

14 February 2019

activation of mitotic cell cycle spindle assembly checkpoint

IEA

1 reference

14 February 2019

The C-terminal half of Saccharomyces cerevisiae Mad1p mediates spindle checkpoint function, chromosome transmission fidelity and CEN association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

nucleocytoplasmic transport

attachment of mitotic spindle microtubules to kinetochore

IGI

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

mitotic spindle assembly checkpoint signaling

MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

14 February 2019

IEA

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40957

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference