Thrombin inhibition by the serpins (Q27006905)

language of work or name

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June 2013

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Journal of Thrombosis and Haemostasis

PubMed

published in

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PubMed

volume

11 Suppl 1

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PubMed

page(s)

254-64

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MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

21 January 2018

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NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation.

21 January 2018

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On the size of the active site in proteases. I. Papain

21 January 2018

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Molecular recognition mechanisms of thrombin

21 January 2018

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Crystal structure of the complex between thrombin and the central "E" region of fibrin

21 January 2018

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The pleiotropic role of the fibrinogen gamma' chain in hemostasis

21 January 2018

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Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation

21 January 2018

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Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha

21 January 2018

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Binding of -thrombin to surface-anchored platelet glycoprotein Ib sulfotyrosines through a two-site mechanism involving exosite I

21 January 2018

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Thrombin domains: structure, function and interaction with platelet receptors

21 January 2018

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Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

21 January 2018

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Crystal structure of thrombin bound to heparin

21 January 2018

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Serpins in thrombosis, hemostasis and fibrinolysis

21 January 2018

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Crystal structure of prethrombin-1

21 January 2018

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Slow thrombin is zymogen-like

21 January 2018

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21 January 2018

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Serpin structure, mechanism, and function

21 January 2018

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Serpin structure, function and dysfunction

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The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

21 January 2018

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Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

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The pH dependence of serpin-proteinase complex dissociation reveals a mechanism of complex stabilization involving inactive and active conformational states of the proteinase which are perturbable by calcium

21 January 2018

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Conformational changes in thrombin when complexed by serpins

21 January 2018

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Thrombin inhibition by serpins disrupts exosite II

21 January 2018

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Cellular internalization and degradation of antithrombin III-thrombin, heparin cofactor II-thrombin, and alpha 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein

21 January 2018

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Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.

21 January 2018

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Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism

21 January 2018

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Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex

21 January 2018

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Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism

21 January 2018

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The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity

21 January 2018

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Inference of macromolecular assemblies from crystalline state

21 January 2018

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The molecular basis of thrombin allostery revealed by a 1.8 A structure of the "slow" form

21 January 2018

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Structural insights into the multiple functions of protein C inhibitor.

21 January 2018

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Crystal structure of protein C inhibitor provides insights into hormone binding and heparin activation

21 January 2018

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Structure of native protein C inhibitor provides insight into its multiple functions

21 January 2018

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The heparin binding site of protein C inhibitor is protease-dependent

21 January 2018

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Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis

21 January 2018

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Vascular dermatan sulfate regulates the antithrombotic activity of heparin cofactor II

21 January 2018

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The interaction of glycosaminoglycans with heparin cofactor II.

21 January 2018

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The heparin binding properties of heparin cofactor II suggest an antithrombin-like activation mechanism

21 January 2018

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Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases

21 January 2018

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Emerging role of serpinE2/protease nexin-1 in hemostasis and vascular biology.

21 January 2018

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Anticoagulant and antithrombotic properties of platelet protease nexin-1

21 January 2018

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