The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPP (Q26830682)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26582333%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Mimi Gao

series ordinal

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26582333%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

1 reference

2015

1 reference

Journal of Diabetes Research

25 October 2015

12 references

13 March 2019

14 March 2019

24 March 2019

5 August 2019

1 October 2019

7 October 2019

10 October 2019

17 November 2019

19 November 2019

20 November 2019

27 January 2021

4 February 2021

14 references

13 March 2019

14 March 2019

24 March 2019

5 August 2019

1 October 2019

7 October 2019

10 October 2019

17 November 2019

19 November 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26582333%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

27 January 2021

4 February 2021

2015

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26582333%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

849017

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26582333%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

7 June 2020

copyright license

12 references

13 March 2019

14 March 2019

24 March 2019

5 August 2019

1 October 2019

7 October 2019

10 October 2019

17 November 2019

19 November 2019

20 November 2019

27 January 2021

on focus list of Wikimedia project

4 February 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Membrane fragmentation by an amyloidogenic fragment of human Islet Amyloid Polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Protein misfolding, functional amyloid, and human disease

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Review: history of the amyloid fibril

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Molecular mechanism of Thioflavin-T binding to amyloid fibrils

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Low levels of asparagine deamidation can have a dramatic effect on aggregation of amyloidogenic peptides: implications for the study of amyloid formation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Direct detection of transient alpha-helical states in islet amyloid polypeptide

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Living with water stress: evolution of osmolyte systems

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Unraveling the Molecular Mechanism of Enthalpy Driven Peptide Folding by Polyol Osmolytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloid aggregation and deposition of human islet amyloid polypeptide at membrane interfaces

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Bayesian total internal reflection fluorescence correlation spectroscopy reveals hIAPP-induced plasma membrane domain organization in live cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Impact of reconstituted cytosol on protein stability.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid polypeptide toxicity and membrane interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The cellular environment stabilizes adenine riboswitch RNA structure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The extracellular protein VlsE is destabilized inside cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Membrane destabilization by monomeric hIAPP observed by imaging fluorescence correlation spectroscopy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Macromolecular crowding as a suppressor of human IAPP fibril formation and cytotoxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

α-helix to β-hairpin transition of human amylin monomer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Common mechanism unites membrane poration by amyloid and antimicrobial peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Adsorption and Orientation of Human Islet Amyloid Polypeptide (hIAPP) Monomer at Anionic Lipid Bilayers: Implications for Membrane-Mediated Aggregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Influence of crowded cellular environments on protein folding, binding, and oligomerization: biological consequences and potentials of atomistic modeling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Cosolvent effects on protein stability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Ionic strength effects on amyloid formation by amylin are a complicated interplay among Debye screening, ion selectivity, and Hofmeister effects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Phosphatidylethanolamine enhances amyloid fiber-dependent membrane fragmentation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The contrasting effect of macromolecular crowding on amyloid fibril formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

How type II diabetes-related islet amyloid polypeptide damages lipid bilayers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Fibril structure of human islet amyloid polypeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

A diversity of assembly mechanisms of a generic amyloid fold

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Macromolecular crowding fails to fold a globular protein in cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Lipid rafts: signaling and sorting platforms of cells and their roles in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloid structure: conformational diversity and consequences

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Biphasic effects of insulin on islet amyloid polypeptide membrane disruption.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Biology of amyloid: structure, function, and regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloidogenic protein-membrane interactions: mechanistic insight from model systems

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Macromolecular crowding converts the human recombinant PrPC to the soluble neurotoxic beta-oligomers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Protein folding stability and dynamics imaged in a living cell

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Crowded cell-like environment accelerates the nucleation step of amyloidogenic protein misfolding.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Functional amyloids as natural storage of peptide hormones in pituitary secretory granules

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Membrane permeabilization by Islet Amyloid Polypeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

A role for helical intermediates in amyloid formation by natively unfolded polypeptides?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Guiding protein aggregation with macromolecular crowding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Structure of alpha-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Sedimentation studies on human amylin fail to detect low-molecular-weight oligomers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Membrane interaction of islet amyloid polypeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Detergent-like actions of linear amphipathic cationic antimicrobial peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

TMAO promotes fibrillization and microtubule assembly activity in the C-terminal repeat region of tau.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Inhibition of glucagon secretion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Predicting the energetics of osmolyte-induced protein folding/unfolding.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Amyloid ion channels: a common structural link for protein-misfolding disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Raft lipids as common components of human extracellular amyloid fibrils

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Ficoll and dextran vs. globular proteins as probes for testing glomerular permselectivity: effects of molecular size, shape, charge, and deformability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Contribution of simple saccharides to the stabilization of amyloid structure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid polypeptide inhibits glucagon release and exerts a dual action on insulin release from isolated islets

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Quantitative protein stability measurement in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The osmophobic effect: natural selection of a thermodynamic force in protein folding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Concentrating hormones into secretory granules: layers of control

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Selective amylin inhibition of the glucagon response to arginine is extrinsic to the pancreas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

The control of protein stability and association by weak interactions with water: how do solvents affect these processes?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid polypeptide. A new beta cell secretory product related to islet amyloid deposits

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid polypeptide: mechanisms of amyloidogenesis in the pancreatic islets and potential roles in diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Steric exclusion is the principal source of the preferential hydration of proteins in the presence of polyethylene glycols

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Excluded-volume effects in living cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Combined effects of agitation, macromolecular crowding, and interfaces on amyloidogenesis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Role of zinc in human islet amyloid polypeptide aggregation.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Visualizing association of lipidated signaling proteins in heterogeneous membranes--partitioning into subdomains, lipid sorting, interfacial adsorption, and protein association

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

THE RELATION OE DIABETES MELLITUS TO LESIONS OF THE PANCREAS. HYALINE DEGENERATION OF THE ISLANDS OE LANGERHANS.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Peptide aggregation in finite systems

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Islet amyloid polypeptide (IAPP) does not inhibit glucose-stimulated insulin secretion from isolated perfused rat pancreas

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Human and rat amylin have no effects on insulin secretion in isolated rat pancreatic islets

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637101

Interaction of hIAPP with model raft membranes and pancreatic beta-cells: cytotoxicity of hIAPP oligomers

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Low-dose pramlintide reduced food intake and meal duration in healthy, normal-weight subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Autophagy in human type 2 diabetes pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Fibrillar islet amyloid polypeptide (amylin) is internalised by macrophages but resists proteolytic degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Phospholipid catalysis of diabetic amyloid assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Amyloidogenic propensities and conformational properties of ProIAPP and IAPP in the presence of lipid bilayer membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Formation of amyloid in human pancreatic islets transplanted to the liver and spleen of nude mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Islet amyloid polypeptide in human insulinomas. Evidence for intracellular amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Amyloid-forming proteins alter the local mechanical properties of lipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Amyloid peptide channels: blockade by zinc and inhibition by Congo red (amyloid channel block).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Acidic pH retards the fibrillization of human Islet Amyloid Polypeptide due to electrostatic repulsion of histidines

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Low pH acts as inhibitor of membrane damage induced by human islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Amylin proprotein processing generates progressively more amyloidogenic peptides that initially sample the helical state

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Elucidating the mechanism of lipid membrane-induced IAPP fibrillogenesis and its inhibition by the red wine compound resveratrol: a synchrotron X-ray reflectivity study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Islet amyloid polypeptide forms rigid lipid-protein amyloid fibrils on supported phospholipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Binding of islet amyloid polypeptide to supported lipid bilayers and amyloid aggregation at the membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Temperature-pressure phase diagram of a heterogeneous anionic model biomembrane system: results from a combined calorimetry, spectroscopy and microscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Cholesterol regulates assembly of human islet amyloid polypeptide on model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Relationship between the protein surface hydrophobicity and its partitioning behaviour in aqueous two-phase systems of polyethyleneglycol-dextran

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Protein crowder charge and protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Accelerated alpha-synuclein fibrillation in crowded milieu

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

The effect of macromolecular crowding on protein aggregation and amyloid fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Inhibition of insulin amyloid formation by small stress molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Trimethylamine-N-oxide-induced folding of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Manipulating the amyloid-beta aggregation pathway with chemical chaperones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Additive transfer free energies of the peptide backbone unit that are independent of the model compound and the choice of concentration scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Cross-amyloid interaction of Aβ and IAPP at lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

The mechanism of insulin action on islet amyloid polypeptide fiber formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Conserved and Cooperative Assembly of Membrane-Bound α-Helical States of Islet Amyloid Polypeptide†

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Viruses, lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Modulation of human IAPP fibrillation: cosolutes, crowders and chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Molecular and cytotoxic properties of hIAPP17–29 and rIAPP17–29 fragments: A comparative study with the respective full-length parent polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Protein Aggregation in Crowded Environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F849017

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

21 January 2018

1 reference

12 December 2020

Pore formation by the cytotoxic islet amyloid peptide amylin

1 reference

12 December 2020

Molecular crowding accelerates fibrillization of alpha-synuclein: could an increase in the cytoplasmic protein concentration induce Parkinson's disease?

1 reference

12 December 2020

Inhibitory action of islet amyloid polypeptide and calcitonin gene-related peptide on release of insulin from the isolated perfused rat pancreas

1 reference

12 December 2020

Protein stabilization by macromolecular crowding through enthalpy rather than entropy

1 reference

12 December 2020

Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro

1 reference

12 December 2020

NMR spectroscopic investigation of early events in IAPP amyloid fibril formation

1 reference

12 December 2020

Homologous islet amyloid polypeptide: effects on plasma levels of glucagon, insulin and glucose in the mouse

1 reference

12 December 2020

Amyloid Fibril Formation from Full-Length and Fragments of Amylin

1 reference

12 December 2020

Comparing the structural properties of human and rat islet amyloid polypeptide by MD computer simulations

1 reference

12 December 2020

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

1 reference

12 December 2020

Amylin inhibits glucose-induced insulin secretion in a dose-dependent manner. Study in the perfused rat pancreas

1 reference

12 December 2020

Macromolecular crowding and protein stability

1 reference

12 December 2020

Cosolvent effects on the fibrillation reaction of human IAPP

1 reference

12 December 2020

Islet amyloid polypeptide inserts into phospholipid monolayers as monomer

1 reference

12 December 2020

B cell granule peptides affect human islet amyloid polypeptide (IAPP) fibril formation in vitro

1 reference

12 December 2020

Natural osmolytes remodel the aggregation pathway of mutant huntingtin exon 1

1 reference

12 December 2020

Failure of islet amyloid polypeptide to inhibit basal and glucose-stimulated insulin secretion in model experiments in mice and rats

1 reference

12 December 2020

Light scattering and phase behavior of lysozyme-poly(ethylene glycol) mixtures

1 reference

12 December 2020

Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide

1 reference

12 December 2020

Fine structure of islets of Langerhans in insular amyloidosis

1 reference

12 December 2020

https://api.fatcat.wiki/v0/release/47v3renpufh4hkgkjdhzbl2a3a

Identifiers

1 reference

30 July 2022

release_47v3renpufh4hkgkjdhzbl2a3a

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/47v3renpufh4hkgkjdhzbl2a3a

30 July 2022

https://api.fatcat.wiki/v0/release/47v3renpufh4hkgkjdhzbl2a3a

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/47v3renpufh4hkgkjdhzbl2a3a

1 reference

30 July 2022