Interleukin 5 (Q2584108)

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mammalian protein found in Homo sapiens
  • TRF
  • interleukin-5
  • T-cell replacing factor
  • IL5
  • B-cell differentiation factor I
  • eosinophil differentiation factor
  • colony-stimulating factor, eosinophil
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Language Label Description Also known as
English
Interleukin 5
mammalian protein found in Homo sapiens
  • TRF
  • interleukin-5
  • T-cell replacing factor
  • IL5
  • B-cell differentiation factor I
  • eosinophil differentiation factor
  • colony-stimulating factor, eosinophil

Statements

molecular function
interleukin-5 receptor binding
determination method
IEA
TAS
3 references
retrieved
31 January 2018
stated in
Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue
UniProt-GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
retrieved
31 January 2018
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
31 January 2018
stated in
Structure analysis of the IL-5 ligand-receptor complex reveals a wrench-like architecture for IL-5Rα
UniProt-GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IPI
retrieved
31 January 2018
stated in
Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit
UniProt-GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IPI
growth factor activity
determination method
IEA
2 references
retrieved
31 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P05113
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
retrieved
31 January 2018
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
protein tyrosine kinase activity
determination method
TAS
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
Ras guanyl-nucleotide exchange factor activity
determination method
TAS
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
cytokine activity
determination method
IEA
2 references
retrieved
31 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P05113
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
cell component
extracellular region
determination method
IDA
IEA
TAS
4 references
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
retrieved
31 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P05113
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
retrieved
31 January 2018
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
retrieved
31 January 2018
stated in
Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IDA
intracellular
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
extracellular space
determination method
IEA
TAS
3 references
retrieved
31 January 2018
stated in
Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue
UniProt-GOA
curator
UniProt
UniProt protein ID
P05113
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
retrieved
31 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P05113
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
biological process
positive regulation of sequence-specific DNA binding transcription factor activity
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
positive regulation of podosome assembly
determination method
IDA
1 reference
retrieved
31 January 2018
stated in
Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes
UniProt-GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IDA
MAPK cascade
determination method
TAS
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
positive regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
immune response
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
positive regulation of cell proliferation
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
positive regulation of eosinophil differentiation
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
positive regulation of peptidyl-tyrosine phosphorylation
determination method
ISS
IEA
2 references
retrieved
31 January 2018
stated in
UniProt-GOA
curator
UniProt
UniProt protein ID
P05113
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
ISS
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
inflammatory response
determination method
IEA
TAS
2 references
retrieved
31 January 2018
stated in
Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5)
UniProt-GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
positive regulation of JAK-STAT cascade
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
peptidyl-tyrosine phosphorylation
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
positive regulation of B cell proliferation
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
positive regulation of immunoglobulin secretion
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
regulation of receptor activity
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA
cytokine-mediated signaling pathway
determination method
IEA
TAS
2 references
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
TAS
retrieved
31 January 2018
stated in
UniProt-GOA
curator
Ensembl
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P05113&geneProductId=UniProtKB:P05113
determination method
IEA

Identifiers

 

Sitelinks

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