Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins (Q24673155)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

12 March 2024

Arthur E. Johnson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

12 March 2024

Rodney K. Tweten

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

12 March 2024

language of work or name

English

0 references

publication date

30 September 2003

0 references

19 September 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

full work available at URL

12 March 2024

https://europepmc.org/articles/pmc208754?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

https://europepmc.org/articles/PMC208754

12 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

https://europepmc.org/articles/PMC208754?pdf=render

12 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

https://doi.org/10.1073/pnas.2033520100

12 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500900

https://pnas.org/doi/pdf/10.1073/pnas.2033520100

12 March 2024

1 reference

DOI

10.1073/PNAS.2033520100

https://api.crossref.org/works/10.1073/PNAS.2033520100

Proceedings of the National Academy of Sciences of the United States of America

12 March 2024

published in

0 references

volume

100

0 references

page(s)

11315-20

0 references

issue

20

0 references

cites work

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 April 2017

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22 April 2017

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Assembly and topography of the prepore complex in cholesterol-dependent cytolysins

22 April 2017

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Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin

28 September 2017

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Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

28 September 2017

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Beta-barrel pore-forming toxins: intriguing dimorphic proteins

28 September 2017

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Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts).

28 September 2017

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28 September 2017

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Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes

28 September 2017

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Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate

28 September 2017

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Channel formation by the glycosylphosphatidylinositol-anchored protein binding toxin aerolysin is not promoted by lipid rafts

28 September 2017

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Molecular analysis of the cytolytic protein ClyA (SheA) from Escherichia coli

28 September 2017

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A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol

28 September 2017

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Interaction of earthworm hemolysin with lipid membranes requires sphingolipids

28 September 2017

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Intermedilysin, a novel cytotoxin specific for human cells secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess

28 September 2017

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Variations of lipid-protein interactions in erythrocyte ghosts as a function of temperature and pH in physiological and non-physiological ranges. A study using a paramagnetic quenching of protein fluorescence by nitroxide lipid analogues

28 September 2017

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The conserved undecapeptide shared by thiol-activated cytolysins is involved in membrane binding

28 September 2017

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A modified theta-toxin produced by limited proteolysis and methylation: a probe for the functional study of membrane cholesterol.

30 May 2018

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Kinetic aspects of the aggregation of Clostridium perfringens theta-toxin on erythrocyte membranes. A fluorescence energy transfer study.

30 May 2018

1 reference

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The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains.

30 May 2018

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Listeriolysin O: cholesterol inhibits cytolysis but not binding to cellular membranes.

21 January 2018

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Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane

21 January 2018

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Oligomerization of Vibrio cholerae cytolysin yields a pentameric pore and has a dual specificity for cholesterol and sphingolipids in the target membrane.

21 January 2018

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Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

21 January 2018

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The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

21 January 2018

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Role of the stereochemistry of the hydroxyl group of cholesterol and the formation of nonbilayer structures in phosphatidylethanolamines

21 January 2018

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12 December 2020

A cytolysin, theta-toxin, preferentially binds to membrane cholesterol surrounded by phospholipids with 18-carbon hydrocarbon chains in cholesterol-rich region

1 reference

12 December 2020

Membrane disorganization induced by perfringolysin O (theta-toxin) of Clostridium perfringens--effect of toxin binding and self-assembly on liposomes

1 reference

12 December 2020

Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion

1 reference

12 December 2020

The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins

1 reference

12 December 2020

Lipids favoring inverted phase enhance the ability of aerolysin to permeabilize liposome bilayers

1 reference

12 December 2020

Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor

1 reference

12 December 2020

Mechanism of the leakage induced on lipid model membranes by the hemolytic protein sticholysin II from the sea anemone Stichodactyla helianthus

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12 December 2020

C-terminal amino acid residues are required for the folding and cholesterol binding property of perfringolysin O, a pore-forming cytolysin

1 reference

12 December 2020

Cross-linking of plasmalemmal cholesterol in lymphocytes induces capping, membrane shedding, and endocytosis through coated pits

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12 December 2020

Action of bacterial cytotoxins on normal mammalian cells and cells with altered membrane lipid composition

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12 December 2020

Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes

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12 December 2020

Staphylococcal alpha-toxin increases the permeability of lipid vesicles by cholesterol- and pH-dependent assembly of oligomeric channels

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12 December 2020