Development of all CD4 T lineages requires nuclear factor TOX (Q24652128)

Journal of Experimental Medicine

GOA release 2020-03-11

author name string

Parinaz Aliahmad

series ordinal

1

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Jonathan Kaye

series ordinal

2

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publication date

21 January 2008

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language of work or name

English

0 references

published in

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volume

205

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issue

1

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page(s)

245-56

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cites work

TOX provides a link between calcineurin activation and CD8 lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

TOX defines a conserved subfamily of HMG-box proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Critical roles for transcription factor GATA-3 in thymocyte development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

NKT cells derive from double-positive thymocytes that are positively selected by CD1d

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

GATA-3 regulates the development and function of invariant NKT cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

T cell receptor antagonist peptides induce positive selection

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

From stem cell to T cell: one route or many?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Commitment issues: linking positive selection signals and lineage diversification in the thymus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Regulation of immunity by self-reactive T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Calcineurin B1 is essential for positive but not negative selection during thymocyte development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

TOX: an HMG box protein implicated in the regulation of thymocyte selection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

CD8 coreceptor extinction in signaled CD4(+)CD8(+) thymocytes: coordinate roles for both transcriptional and posttranscriptional regulatory mechanisms in developing thymocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Activation events during thymic selection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

CD4/CD8 lineage commitment: matching fate with competence

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Distinct stage-specific cis-active transcriptional mechanisms control expression of T cell coreceptor CD8 alpha at double- and single-positive stages of thymic development

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Commitment to the T cell receptor-alpha beta or -gamma delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

A molecular map of T cell development.

30 May 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

A molecular chart of thymocyte positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Hierarchical interactions control CD4 gene expression during thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Thymocyte negative selection is mediated by protein kinase C- and Ca2+-dependent transcriptional induction of bim [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Regulation of lineage commitment distinct from positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20071944

Role of TCR specificity in CD4 versus CD8 lineage commitment.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234360

Identification of a naturally occurring ligand for thymic positive selection

28 November 2018

1 reference

12 December 2020

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

12 December 2020

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

1 reference

12 December 2020

Transcriptional regulation of CD4 gene expression by T cell factor-1/beta-catenin pathway

1 reference

12 December 2020

Progenies of fetal thymocytes are the major source of CD4-CD8+ alpha alpha intestinal intraepithelial lymphocytes early in ontogeny

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20071944

1 reference

1 reference

1 reference

PubMed publication ID

18195075

1 reference