Suppression of tumorigenesis by the p53 target PUMA (Q24563144)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Suppression of tumorigenesis by the p53 target PUMA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

5

Gregory J Hannon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Michael T Hemann

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Jack T Zilfou

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Zhen Zhao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Scott W Lowe

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

10 June 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

29 December 2019

language of work or name

English

0 references

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

9333-9338

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

29 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

PUMA, a novel proapoptotic gene, is induced by p53

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

PUMA induces the rapid apoptosis of colorectal cancer cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

24 March 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Control of apoptosis by p53.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Dissecting p53 tumor suppressor functions in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

B-cell lymphoma-associated hemophagocytic syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Chromosome 19q Deletions in Human Gliomas Overlap Telomeric to D19S219 and May Target a 425 kb Region Centromeric to D19S112

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=438977

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0403286101

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0403286101

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0403286101

21 January 2018

12 December 2020

Loss of heterozygosity at 19q13.3 is associated with locally aggressive neuroblastoma

1 reference

12 December 2020

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

12 December 2020

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

1 reference

12 December 2020

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0403286101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15192153%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

15192153

1 reference