The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men (Q24561868)

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English	The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men	scientific article

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scholarly article

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The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men (English)

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pharmacokinetics

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based on heuristic

inferred from title

Shalender Bhasin

14

object named as

Shalender Bhasin

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Shehzad Basaria

1

object named as

Shehzad Basaria

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Thomas W Storer

5

object named as

Thomas W Storer

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4

object named as

Katie Orwoll

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6

object named as

Renee Miciek

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Jagadish Ulloor

7

object named as

Jagadish Ulloor

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author name string

Lauren Collins

2

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E Lichar Dillon

3

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Anqi Zhang

8

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Richard Eder

9

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Heather Zientek

10

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Gilad Gordon

11

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Syed Kazmi

12

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Melinda Sheffield-Moore

13

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language of work or name

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publication date

January 2013

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The Journals of Gerontology

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68

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1

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87-95

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Adverse events associated with testosterone administration

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Selective androgen receptor modulators in preclinical and clinical development

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The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial.

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27 September 2017

Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation

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27 September 2017

Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts

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27 September 2017

The Role of GH and IGF-I in Mediating Anabolic Effects of Testosterone on Androgen-Responsive Muscle

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27 September 2017

Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology

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27 September 2017

A novel spreadsheet method for calculating the free serum concentrations of testosterone, dihydrotestosterone, estradiol, estrone and cortisol: with illustrative examples from male and female populations

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27 September 2017

Tests of muscle strength and physical function: reliability and discrimination of performance in younger and older men and older men with mobility limitations

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27 September 2017

An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate

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Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging

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Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway

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27 September 2017

Androgens and coronary artery disease

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27 September 2017

Testosterone up-regulates scavenger receptor BI and stimulates cholesterol efflux from macrophages

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27 September 2017

Testosterone administration to older men improves muscle function: molecular and physiological mechanisms

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High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport

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Prevention of coronary heart disease by raising high-density lipoprotein cholesterol?

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Charting the fate of the "good cholesterol": identification and characterization of the high-density lipoprotein receptor SR-BI.

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27 September 2017

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.

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27 September 2017

Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis

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27 September 2017

Effect of sex hormones on protamine inactivated and resistant postheparin plasma lipases

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27 September 2017

In vivo regulation of apolipoprotein A-I gene expression by estradiol and testosterone occurs by different mechanisms in inbred strains of mice

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27 September 2017

Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement

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30 May 2018

Predictors of skeletal muscle mass in elderly men and women.

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30 May 2018

Distribution of different fibre types in human skeletal muscles. A statistical and computational study of the fibre type arrangement in m. vastus lateralis of young, healthy males.

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30 May 2018

Contrasting effects of testosterone and stanozolol on serum lipoprotein levels.

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19 June 2018

Interrelationships of serum testosterone and free testosterone index with FFM and strength in aging men.

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21 January 2018

Endogenous testosterone levels, physical performance, and fall risk in older men.

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Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study

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21 January 2018

Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T.

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21 January 2018

Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle

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21 January 2018

Testosterone dose-dependently increases maximal voluntary strength and leg power, but does not affect fatigability or specific tension

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21 January 2018

Effects of an oral androgen on muscle and metabolism in older, community-dwelling men.

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21 January 2018

Testosterone-induced increase in muscle size in healthy young men is associated with muscle fiber hypertrophy

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2FGLS078

21 January 2018

Testosterone-induced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men.

1 reference

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21 January 2018

Effects of testosterone replacement in hypogonadal men.

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28 November 2018

Cachexia: new advances in the management of wasting diseases

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12 December 2020

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Epidemiology of sarcopenia

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12 December 2020

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Leg extensor power and functional performance in very old men and women

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12 December 2020

based on heuristic

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Identifiers

10.1093/GERONA/GLS078

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release_2gdxgcrtyrhz5baxjc7fvwxvgm

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https://api.fatcat.wiki/v0/release/2gdxgcrtyrhz5baxjc7fvwxvgm

24 November 2022

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