Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin S (Q24528220)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7575468%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

title

Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin S (English)

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21 October 2019

1

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21 October 2019

author name string

C Haass

2

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21 October 2019

C A Lemere

3

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21 October 2019

G P Shi

4

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21 October 2019

W S Wong

5

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21 October 2019

D B Teplow

6

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21 October 2019

D J Selkoe

7

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21 October 2019

H A Chapman

8

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21 October 2019

language of work or name

English

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publication date

1 October 1995

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21 October 2019

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21 October 2019

volume

311 ( Pt 1)

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21 October 2019

page(s)

299-305

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Human cathepsin S: chromosomal localization, gene structure, and tissue distribution

21 October 2019

cites work

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The lysosomal cysteine protease, cathepsin S, is increased in Alzheimer's disease and Down syndrome brain. An immunocytochemical study

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24 March 2017

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Phylogenetic conservation of cysteine proteinases. Cloning and expression of a cDNA coding for human cathepsin S

24 March 2017

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24 March 2017

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27 September 2017

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Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

27 September 2017

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Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

27 September 2017

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Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

27 September 2017

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Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins.

27 September 2017

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The specificity of bovine spleen cathepsin S. A comparison with rat liver cathepsins L and B.

27 September 2017

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A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein

27 September 2017

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27 September 2017

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27 September 2017

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Processing of the papain precursor. Purification of the zymogen and characterization of its mechanism of processing

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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30 May 2018

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30 May 2018

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Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

30 May 2018

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Cathepsin S. The cysteine proteinase from bovine lymphoid tissue is distinct from cathepsin L (EC 3.4.22.15).

30 May 2018

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A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

30 May 2018

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Clipsin, a chymotrypsin-like protease in rat brain which is irreversibly inhibited by alpha-1-antichymotrypsin.

30 May 2018

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Inhibitor studies indicate that active cathepsin L is probably essential to its own processing in cultured fibroblasts

30 May 2018

1 reference

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Cleavage of amyloid beta peptide during constitutive processing of its precursor

30 May 2018

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Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

30 May 2018

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Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

30 May 2018

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Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

30 May 2018

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Human brain peptidase activity with the specificity to generate the N-terminus of the Alzheimer β-amyloid protein from its precursor

30 May 2018

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

30 May 2018

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

30 May 2018

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A calcium-stimulated serine protease from monkey brain degrades the beta-amyloid precursor protein.

30 May 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

30 May 2018

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Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

30 May 2018

1 reference

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Enzymatic generation of the amino terminus of the beta-amyloid peptide.

29 November 2018

1 reference

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Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor.

29 November 2018

1 reference

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Differential distribution of messenger RNAs for cathepsins B, L and S in adult rat brain: an in situ hybridization study.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136152

Functional expression of human cathepsin S in Saccharomyces cerevisiae. Purification and characterization of the recombinant enzyme

29 November 2018

1 reference

12 December 2020

In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64

1 reference

12 December 2020

Putative N-terminal splitting enzyme of amyloid A4 peptides is the multicatalytic proteinase, ingensin, which is widely distributed in mammalian cells

1 reference

12 December 2020

Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ3110299

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7575468%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7575468%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference