Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors (Q24338232)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715146%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors (English)

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3 January 2020

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MutS homolog 6

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Werner syndrome RecQ like helicase

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MutS homolog 3

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3'-5' DNA helicase activity

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5

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3 January 2020

author name string

Nurten Saydam

1

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3 January 2020

Radhakrishnan Kanagaraj

2

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3 January 2020

Tobias Dietschy

3

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3 January 2020

Patrick L Garcia

4

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3 January 2020

Igor Shevelev

6

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3 January 2020

Igor Stagljar

7

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3 January 2020

Pavel Janscak

8

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3 January 2020

language of work or name

English

0 references

publication date

22 August 2007

1 reference

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3 January 2020

published in

Nucleic Acids Research

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3 January 2020

volume

35

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3 January 2020

page(s)

5706-5716

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3 January 2020

issue

17

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describes a project that uses

3 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2034464/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats

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RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination

19 March 2017

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Asymmetry of DNA replication fork progression in Werner's syndrome

19 March 2017

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Characterization and mutational analysis of the RecQ core of the bloom syndrome protein

19 March 2017

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WRN interacts physically and functionally with the recombination mediator protein RAD52

19 March 2017

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Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

19 March 2017

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Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

19 March 2017

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The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

19 March 2017

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Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis

19 March 2017

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Ku complex interacts with and stimulates the Werner protein

19 March 2017

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MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

19 March 2017

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The Werner syndrome protein is a DNA helicase

19 March 2017

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Mutator phenotype of Werner syndrome is characterized by extensive deletions

19 March 2017

1 reference

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The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

19 March 2017

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Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination

19 March 2017

1 reference

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SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination

19 March 2017

1 reference

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Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2

19 March 2017

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The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links

19 March 2017

1 reference

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19 March 2017

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Pathways and functions of the Werner syndrome protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation

19 March 2017

1 reference

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The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair

19 March 2017

1 reference

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hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA

19 March 2017

1 reference

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hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

19 March 2017

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Positional cloning of the Werner's syndrome gene

19 March 2017

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Telomere dysfunction as a cause of genomic instability in Werner syndrome

7 April 2017

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The multifaceted mismatch-repair system

27 September 2017

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Accumulation of Werner protein at DNA double-strand breaks in human cells

27 September 2017

1 reference

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MutSalpha binds to and promotes synapsis of transcriptionally activated immunoglobulin switch regions

27 September 2017

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Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

27 September 2017

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Distinct roles for the Saccharomyces cerevisiae mismatch repair proteins in heteroduplex rejection, mismatch repair and nonhomologous tail removal

27 September 2017

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Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1

27 September 2017

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The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase

27 September 2017

1 reference

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Linkage between Werner syndrome protein and the Mre11 complex via Nbs1.

27 September 2017

1 reference

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The Bloom's syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6.

27 September 2017

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DNA repair defects in colon cancer

27 September 2017

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Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1.

27 September 2017

1 reference

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Homologous recombination resolution defect in werner syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

hMutSbeta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Werner syndrome cells are sensitive to DNA cross-linking drugs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Mismatch repair in extracts of Werner syndrome cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Syndromes of accelerated aging

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Endonucleolytic function of MutLalpha in human mismatch repair.

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKM500

DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKM500

Quantitative beta-galactosidase assay suitable for high-throughput applications in the yeast two-hybrid system.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034464

Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase

29 November 2018

1 reference

12 December 2020

A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture

1 reference

12 December 2020

Cytogenetic aspects of Werner syndrome

1 reference

12 December 2020

Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

1 reference

12 December 2020

Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence

1 reference

12 December 2020

Msh2 deficiency leads to chromosomal abnormalities, centrosome amplification, and telomere capping defect

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKM500

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715146%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715146%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference