Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells (Q24338149)

2

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S de Beaucé

3

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D Monté

4

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E Leteurtre

5

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I van Seuningen

6

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G Huet

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P Pigny

Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state

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language of work or name

English

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publication date

2 June 2011

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published in

Oncogene

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volume

30

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page(s)

2514-25

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issue

22

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cites work

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Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancer

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MUC1 regulates nuclear localization and function of the epidermal growth factor receptor

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Transport of galectin-3 between the nucleus and cytoplasm. I. Conditions and signals for nuclear import

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Apical sorting by galectin-3-dependent glycoprotein clustering

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Galectin-3: an open-ended story

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Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

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Subsets of epidermal growth factor receptors during activation and endocytosis

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Galectin-3 mediates the endocytosis of beta-1 integrins by breast carcinoma cells

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Galectin-3 regulates myofibroblast activation and hepatic fibrosis

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Mucins in cancer: protection and control of the cell surface

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Characterization of a novel tripartite nuclear localization sequence in the EGFR family.

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Classical Chemotherapy: Mechanisms, Toxicities and the Therapeutc Window

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Secretion of the galectin family of mammalian carbohydrate-binding proteins

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Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression.

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Gene-expression signature of adhesion/growth-regulatory tissue lectins (galectins) in transitional cell cancer and its prognostic relevance

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Quantitative RT-PCR assay for MUC3 and VEGF mRNA in renal clear cell carcinoma: relationship with nuclear grade and prognosis.

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MUC1 expression is correlated with nuclear grade and tumor progression in pT1 renal clear cell carcinoma

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The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin

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Nuclear localization of EGF receptor and its potential new role as a transcription factor

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Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1.

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Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray.

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Differential MUC 1 expression in normal and neoplastic human pancreatic tissue. An immunohistochemical study of 60 samples

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Pathogenesis of invasive micropapillary carcinoma: role of MUC1 glycoprotein

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Serine protease inhibitor Kazal type 1 promotes proliferation of pancreatic cancer cells through the epidermal growth factor receptor

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Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells.

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MUC1 is a novel regulator of ErbB1 receptor trafficking

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The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop

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Analysis of the role of type 1 core O-glycans in the binding of anti-MUC1 antibodies by cytofluorometry and synthetic peptide/glycopeptide binding inhibition studies

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Characterization of a Panel of Monoclonal Antibodies Using GalNAc Glycosylated Peptides and Recombinant MUC1

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Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland

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Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity

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Galectin-4-regulated delivery of glycoproteins to the brush border membrane of enterocyte-like cells

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The K protein domain that recruits the interleukin 1-responsive K protein kinase lies adjacent to a cluster of c-Src and Vav SH3-binding sites. Implications that K protein acts as a docking platform

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Diagnostic value of mucins (MUC1, MUC2 and MUC5AC) expression profile in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas

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Nuclear trafficking of the epidermal growth factor receptor family membrane proteins

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Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response

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Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.

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Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion.

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Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis.

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Identifiers

DOI

10.1038/ONC.2010.631

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

4218874

1032916154

0 references

4218874

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference