Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox (Q24337933)

https://api.crossref.org/works/10.1126/SCIENCE.1672471

25 October 2022

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GOA release 2020-03-11

multicellular organism development

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chromosomal deletion syndrome

GOA release 2020-03-11

phenotype

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based on heuristic

inferred from title

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25 October 2022

homeobox

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25 October 2022

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A. L. Joyner

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25 October 2022

K. Herrup

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25 October 2022

B. A. Auerbach

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C. A. Davis

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J. Rossant

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https://syndication.highwire.org/content/doi/10.1126/science.1672471

25 October 2022

publication date

8 March 1991

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language of work or name

English

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work available at URL

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https://api.crossref.org/works/10.1126/SCIENCE.1672471

25 October 2022

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251

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issue

4998

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page(s)

1239-43

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Experimental reorganization of the cerebellar cortex. I. Morphological effects of elimination of all microneurons with prolonged x‐irradiation started at birth

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Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development

25 October 2022

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Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain

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The sequence specificity of homeodomain-DNA interaction

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Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein

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A zebrafish engrailed-like homeobox sequence expressed during embryogenesis

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Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts

25 October 2022

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Expression of an engrailed-like gene during development of the early embryonic chick nervous system

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The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain

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Granule cell as a site of gene action in the weaver mouse cerebellum: evidence from heterozygous mutant chimeras

25 October 2022

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Regional differences in cytoarchitecture of the weaver cerebellum suggest a new model for weaver gene action

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Strain-specific variations in the folial pattern of the mouse cerebellum

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Expression during embryogenesis of a mouse gene with sequence homology to the Drosophila engrailed gene

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En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis

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Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells

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The engrailed locus of Drosophila: in situ localization of transcripts reveals compartment-specific expression

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Further studies of the engrailed phenotype in Drosophila

25 October 2022

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On the role of the engrailed+ gene in the internal organs of Drosophila

25 October 2022

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Chromosomal localization of the human homeo box-containing genes, EN1 and EN2

25 October 2022

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Identification and mapping of a mouse gene influencing cerebellar folial pattern

25 October 2022

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In situ hybridization patterns of zebrafish homeobox genes homologous to Hox-2.1 and En-2 of mouse

25 October 2022

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The engrailed locus of Drosophila: structural analysis of an embryonic transcript

25 October 2022

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Abnormal rate of granule cell migration in the cerebellum of “weaver” mutant mice

25 October 2022

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Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

25 October 2022

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A single amino acid can determine the DNA binding specificity of homeodomain proteins.

25 October 2022

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Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

25 October 2022

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