Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase (Q24336613)

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3 January 2020

title

Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase (English)

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autocrine motility factor receptor

3 January 2020

main subject

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ubiquitin-protein transferase activity

GOA release 2020-03-11

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GOA release 2020-03-11

author

Wei Qi

3

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3 January 2020

Bao-Liang Song

10

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3 January 2020

author name string

Jian Cao

1

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3 January 2020

Jiang Wang

2

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3 January 2020

Hong-Hua Miao

4

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3 January 2020

Jing Wang

5

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3 January 2020

Liang Ge

6

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3 January 2020

Russell A DeBose-Boyd

7

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3 January 2020

Jing-Jie Tang

8

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3 January 2020

Bo-Liang Li

9

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3 January 2020

publication date

1 August 2007

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3 January 2020

language of work or name

0 references

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3 January 2020

volume

6

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3 January 2020

issue

2

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3 January 2020

page(s)

115-128

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Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

3 January 2020

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Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol

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Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

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7 January 2021

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