The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85 (Q24319764)

10

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author name string

Thomas Oellerich

1

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Vanessa Bremes

2

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Konstantin Neumann

3

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Hanibal Bohnenberger

4

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Kai Dittmann

5

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He-Hsuan Hsiao

6

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Michael Engelke

7

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Tim Schnyder

8

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Facundo D Batista

9

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Jürgen Wienands

Prolectin, a glycan-binding receptor on dividing B cells in germinal centers

11

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language of work or name

English

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publication date

31 August 2011

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published in

The EMBO Journal

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volume

30

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page(s)

3620-34

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issue

17

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cites work

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The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

19 March 2017

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Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl

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SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

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SLP-65 phosphorylation dynamics reveals a functional basis for signal integration by receptor-proximal adaptor proteins

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A leucine zipper in the N terminus confers membrane association to SLP-65

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Linking the T Cell Surface Protein CD2 to the Actin-capping Protein CAPZ via CMS and CIN85

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Identification of UNC119 as a novel activator of SRC-type tyrosine kinases

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Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes

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Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

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Identification of the SH2 domain binding protein of Bruton's tyrosine kinase as BLNK--functional significance of Btk-SH2 domain in B-cell antigen receptor-coupled calcium signaling

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BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

19 March 2017

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BASH, a novel signaling molecule preferentially expressed in B cells of the bursa of Fabricius

19 March 2017

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A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

19 March 2017

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The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain

19 March 2017

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Regulation of actin assembly associated with protrusion and adhesion in cell migration

19 March 2017

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Emerging roles of Ruk/CIN85 in vesicle-mediated transport, adhesion, migration and malignancy.

7 April 2017

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The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor

27 September 2017

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Recruitment of the cytoplasmic adaptor Grb2 to surface IgG and IgE provides antigen receptor-intrinsic costimulation to class-switched B cells

27 September 2017

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CIN85 associates with endosomal membrane and binds phosphatidic acid

27 September 2017

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27 September 2017

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Conformational plasticity and navigation of signaling proteins in antigen-activated B lymphocytes

27 September 2017

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Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

27 September 2017

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Calcium signalling and cell-fate choice in B cells

27 September 2017

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Ca(2+) signaling in antigen receptor-activated B lymphocytes

27 September 2017

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27 September 2017

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Antigen-receptor signaling to nuclear factor kappa B.

27 September 2017

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ITAM-mediated tonic signalling through pre-BCR and BCR complexes

27 September 2017

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Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.

27 September 2017

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Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening

27 September 2017

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CIN85/CMS family of adaptor molecules

27 September 2017

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27 September 2017

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Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membrane

27 September 2017

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Functional complementation of BLNK by SLP-76 and LAT linker proteins

27 September 2017

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The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells

27 September 2017

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Different protein tyrosine kinases are required for B cell antigen receptor-mediated activation of extracellular signal-regulated kinase, c-Jun NH2-terminal kinase 1, and p38 mitogen-activated protein kinase.

27 September 2017

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27 September 2017

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27 September 2017

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CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway

27 September 2017

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B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice

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B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase

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