Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro (Q24310177)

4 July 2017

Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro (English)

1 reference

Telomerase reverse transcriptase

4 July 2017

1 reference

Protection of telomeres 1

GOA release 2020-03-11

1 reference

positive regulation of DNA strand elongation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

3

Thomas R Cech

1 reference

4 July 2017

2

Elaine R Podell

1 reference

4 July 2017

1

Arthur J Zaug

1 reference

PubMed ID

16043710

4 July 2017

language of work or name

English

0 references

publication date

25 July 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 July 2017

1 reference

4 July 2017

102

1 reference

4 July 2017

10864-10869

1 reference

4 July 2017

31

1 reference

Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro

4 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Normal human chromosomes have long G-rich telomeric overhangs at one end

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Crystal structure of parallel quadruplexes from human telomeric DNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Switching human telomerase on and off with hPOT1 protein in vitro

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Pot1, the putative telomere end-binding protein in fission yeast and humans

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

DNA structure-dependent recruitment of telomeric proteins to single-stranded/double-stranded DNA junctions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Interaction of telomestatin with the telomeric single-strand overhang.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein UP1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Heterogeneous nuclear ribonucleoprotein A1 and UP1 protect mammalian telomeric repeats and modulate telomere replication in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Following G-quartet formation by UV-spectroscopy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Modulation of telomerase activity by telomere DNA-binding proteins in Oxytricha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Euplotes telomerase: evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

dGTP-dependent processivity and possible template switching of euplotes telomerase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Utilization of ribonucleotides and RNA primers by Tetrahymena telomerase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Monovalent cation-induced structure of telomeric DNA: the G-quartet model

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Inhibition of telomerase by G-quartet DNA structures

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

27 September 2017

Telomerase is processive

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Determining the folding and unfolding rate constants of nucleic acids by biosensor. Application to telomere G-quadruplex.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Processive utilization of the human telomerase template: lack of a requirement for template switching

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1180509

Effect of DNA secondary structure on human telomerase activity

29 November 2018

1 reference

12 December 2020

Stability of intramolecular DNA quadruplexes: comparison with DNA duplexes

1 reference

12 December 2020

Destruction of quadruplex by proteins, and its biological implications in replication and telomere maintenance

1 reference

12 December 2020

X-ray fiber diffraction and model-building study of polyguanylic acid and polyinosinic acid

1 reference

12 December 2020

Structure and stability of human telomeric sequence

1 reference

12 December 2020

Characterization and thermodynamic properties of quadruplex/duplex competition

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0504744102

1 reference

OpenCitations bibliographic resource ID

4 July 2017

0 references

2297596

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

4 July 2017

1 reference

PubMed ID

16043710