Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B (Q24309564)

GOA release 2020-03-11

author

Phillip Thomas Hawkins

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author name string

K E Anderson

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J Coadwell

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L R Stephens

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

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publication date

4 June 1998

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language of work or name

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8

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issue

12

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page(s)

684-91

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cites work

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7 January 2021

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

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Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

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Role of translocation in the activation and function of protein kinase B

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Protein Kinase B and Rac Are Activated in Parallel within a Phosphatidylinositide 3OH-kinase-controlled Signaling Pathway

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Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

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Mechanism of activation of protein kinase B by insulin and IGF-1

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

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Phosphorylation and activation of p70s6k by PDK1

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Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membrane

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Lipid-Regulated Kinases: Some Common Themes at Last

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Insulin stimulates p70 S6 kinase in the nucleus of cells

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The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

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Activation of Raf as a result of recruitment to the plasma membrane

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

9637919

1 reference

Consolidated OpenCitations Corpus – April 2017