Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress (Q24298251)

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Linda V Hjørnevik

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Vibeke H Bull

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Lise Fismen

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Ann K Frøyset

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Darina Gromyko

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Therese Solstad

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Kari Espolin Fladmark

The characterization of the invasion phenotype of uveal melanoma tumour cells shows the presence of MUC18 and HMG-1 metastasis markers and leads to the identification of DJ-1 as a potential serum biomarker

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language of work or name

English

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publication date

April 2010

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published in

Proteomics

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volume

10

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page(s)

1494-504

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issue

7

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cites work

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DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

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DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism

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The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications

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The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells

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Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

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DJ-1, a novel regulator of the tumor suppressor PTEN.

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Acetylation is indispensable for p53 activation

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Sumoylation is critical for DJ-1 to repress p53 transcriptional activity.

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Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits.

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Proteomic response of human neuroblastoma cells to azaspiracid-1.

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Identification of a novel phosphorylation site of acyl-CoA binding protein (ACBP) in nodularin-induced apoptotic hepatocytes

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NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities

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A systematic MS-based approach for identifying in vitro substrates of PKA and PKG in rat uteri

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Deacetylation of p53 modulates its effect on cell growth and apoptosis

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DJ-1 modulates UV-induced oxidative stress signaling through the suppression of MEKK1 and cell death

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Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

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Proteomic identification of p53-dependent protein phosphorylation.

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Ultrarapid caspase-3 dependent apoptosis induction by serine/threonine phosphatase inhibitors

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DJ-1 has a role in antioxidative stress to prevent cell death

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The human Mi-2/NuRD complex and gene regulation

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The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

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Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death

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Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

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A quantitative atlas of mitotic phosphorylation

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DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses

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Wild-type p53-mediated induction of rat mdr1b expression by the anticancer drug daunorubicin

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DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor

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7 January 2021

DJ-1 decreases Bax expression through repressing p53 transcriptional activity

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Metastasis tumor antigens, an emerging family of multifaceted master coregulators.

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Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis

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7 January 2021

DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells

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7 January 2021

Signaling pathways activated by daunorubicin

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7 January 2021

Are Parkinson disease patients protected from some but not all cancers?

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DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

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7 January 2021

PARK7 and nucleoside diphosphate kinase A as plasma markers for the early diagnosis of stroke.

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7 January 2021