K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function (Q24298001)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20802526%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function (English)

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13 February 2020

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3

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13 February 2020

Neus Agell

5

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13 February 2020

author name string

B Alvarez-Moya

1

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13 February 2020

C López-Alcalá

2

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13 February 2020

O Bachs

4

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13 February 2020

language of work or name

English

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publication date

30 August 2010

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13 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20802526%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

29

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13 February 2020

page(s)

5911-5922

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issue

44

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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

13 February 2020

cites work

1 reference

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

20 April 2017

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Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling

20 April 2017

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Modulation of the Ras/Raf/MEK/ERK pathway by Ca(2+), and calmodulin

20 April 2017

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The diverging roles of calmodulin and PKC in the regulation of p21 intracellular localization.

21 January 2018

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PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.

21 January 2018

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Calmodulin inhibitor W13 induces sustained activation of ERK2 and expression of p21(cip1).

21 January 2018

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Ca2+-calmodulin and protein kinase Cs: a hypothetical synthesis of their conflicting convergences on shared substrate domains

21 January 2018

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Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

21 January 2018

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Galectin-1 Augments Ras Activation and Diverts Ras Signals to Raf-1 at the Expense of Phosphoinositide 3-Kinase

21 January 2018

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Constitutive association of c-N-Ras with c-Raf-1 and protein kinase C epsilon in latent signaling modules

21 January 2018

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Ras proteins: different signals from different locations

21 January 2018

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K-ras is an essential gene in the mouse with partial functional overlap with N-ras

21 January 2018

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Growth factor-dependent AKT activation and cell migration requires the function of c-K(B)-Ras versus other cellular ras isoforms

21 January 2018

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Characterization of p21Ras-mediated apoptosis induced by protein kinase C inhibition and application to human tumor cell lines

21 January 2018

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Identification of essential interacting elements in K-Ras/calmodulin binding and its role in K-Ras localization

21 January 2018

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Regulation of the cell cycle by calcium and calmodulin

21 January 2018

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How do small GTPase signal transduction pathways regulate cell cycle entry?

21 January 2018

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Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation

21 January 2018

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Calmodulin modulates H-Ras mediated Raf-1 activation.

21 January 2018

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Ras proteins: paradigms for compartmentalised and isoform-specific signalling.

21 January 2018

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Electrostatic interactions positively regulate K-Ras nanocluster formation and function

21 January 2018

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Direct visualization of Ras proteins in spatially distinct cell surface microdomains

21 January 2018

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Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

21 January 2018

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Binding of calmodulin to the carboxy-terminal region of p21 induces nuclear accumulation via inhibition of protein kinase C-mediated phosphorylation of Ser153.

21 January 2018

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Integrating the MAP kinase signal into the G1 phase cell cycle machinery

21 January 2018

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The multifunctional Ca2+/calmodulin-dependent protein kinases

21 January 2018

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K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3.

21 January 2018

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The murine N-ras gene is not essential for growth and development

21 January 2018

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Calmodulin prevents activation of Ras by PKC in 3T3 fibroblasts

21 January 2018

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PKCdelta survival signaling in cells containing an activated p21Ras protein requires PDK1.

21 January 2018

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Protein kinase C delta is required for survival of cells expressing activated p21RAS

21 January 2018

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Stimulation of p21 ras upon T-cell activation

21 January 2018

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Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch

21 January 2018

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PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

31 March 2020

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Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.298

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20802526%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 February 2020

0 references

1 reference