The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6) (Q24294810)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

ETS variant transcription factor 6

31 October 2019

main subject

1 reference

L3MBTL1, histone methyl-lysine binding protein

GOA release 2020-03-11

1 reference

negative regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Joseph M. Scandura

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Donal MacGrogan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

author name string

Piernicola Boccuni

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Stephen D Nimer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

publication date

14 February 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

31 October 2019

language of work or name

English

0 references

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12588862%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

278

1 reference

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31 October 2019

issue

17

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31 October 2019

page(s)

15412-15420

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A human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomes

31 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

A temperature-sensitive brain tumor suppressor mutation of Drosophila melanogaster: developmental studies and molecular localization of the gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The Drosophila melanogaster tumor suppressor gene lethal(3)malignant brain tumor encodes a proline-rich protein with a novel zinc finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Identification of candidate genes on chromosome band 20q12 by physical mapping of translocation breakpoints found in myeloid leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Chromatin-silencing mechanisms in Drosophila maintain patterns of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Locking in stable states of gene expression: transcriptional control during Drosophila development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

White gene expression, repressive chromatin domains and homeotic gene regulation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

PcG complexes and chromatin silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Molecular characterization of h‐l(3)mbt‐like: a new member of the human mbt family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Identification of SCML2, a second human gene homologous to the Drosophila sex comb on midleg (Scm): A new gene cluster on Xp22

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

A Domain Shared by the Polycomb Group Proteins Scm and ph Mediates Heterotypic and Homotypic Interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

SAM: a novel motif in yeast sterile and Drosophila polyhomeotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

SAM as a protein interaction domain involved in developmental regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Three distinct domains in TEL-AML1 are required for transcriptional repression of the IL-3 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The Drosophila Polycomb Group Gene pleiohomeotic Encodes a DNA Binding Protein with Homology to the Transcription Factor YY1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The ets Family Member Tel Binds to the Fli-1 Oncoprotein and Inhibits Its Transcriptional Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

TEL is a sequence-specific transcriptional repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

General transcription factors bind promoters repressed by Polycomb group proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Posttranslational modification of TEL and TEL/AML1 by SUMO-1 and cell-cycle-dependent assembly into nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Linking the Rb and polycomb pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Polycombing the Genome: PcG, trxG, and Chromatin Silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Stabilization of chromatin structure by PRC1, a Polycomb complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Chromosome 20 deletions in myeloid malignancies: reduction of the common deleted region, generation of a PAC/BAC contig and identification of candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Myeloproliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Hematologic disorders associated with deletions of chromosome 20q: a clinicopathologic study of 107 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Refinement of the Smallest Commonly Deleted Segment of Chromosome 20 in Malignant Myeloid Diseases and Development of a PAC-Based Physical and Transcription Map

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The ETS-domain transcription factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200

Activation of ternary complex factor Elk-1 by MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300592200