Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling (Q24291810)

GOA release 2020-03-11

Phospholipase C gamma 2

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peptidyl-tyrosine phosphorylation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

R Rodriguez

1

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M Matsuda

2

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O Perisic

3

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J Bravo

4

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A Paul

5

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N P Jones

6

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Y Light

7

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K Swann

8

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R L Williams

9

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M Katan

Journal of Biological Chemistry

10

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language of work or name

English

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publication date

21 December 2001

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published in

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volume

276

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page(s)

47982-92

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issue

51

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cites work

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Phospholipase C-gamma as a signal-transducing element

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Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development

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Regulation of the phospholipase C-gamma2 pathway in B cells

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BLNK: connecting Syk and Btk to calcium signals

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A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

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Encoding of Ca2+ signals by differential expression of IP3 receptor subtypes

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BLNK: a central linker protein in B cell activation

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BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

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Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis.

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A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells

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Regulation of oxidative stress-induced calcium release by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase in B cells

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Cooperation of tyrosine kinases p72syk and p53/56lyn regulates calcium mobilization in chicken B cell oxidant stress signaling

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PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

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Platelet-derived growth factor increases the in vivo activity of phospholipase C-gamma 1 and phospholipase C-gamma 2

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Real time fluorescence imaging of PLC gamma translocation and its interaction with the epidermal growth factor receptor

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Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

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Hematopoietic cell-specific adapter proteins, SLP-76 and BLNK, effectively activate NF-AT as well as NF-kappaB by Syk and Tec PTKs in non-lymphoid cell lines

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In vitro tyrosine phosphorylation of PLC-gamma 1 and PLC-gamma 2 by src-family protein tyrosine kinases

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Oncogenic kinase signalling

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Phosphorylation of phospholipase Cgamma1 on tyrosine residue 783 by platelet-derived growth factor regulates reorganization of the cytoskeleton

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Genetic analysis of tyrosine kinase function in B cell development

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Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases

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Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

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Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

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Families of phosphoinositide-specific phospholipase C: structure and function

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7 January 2021

Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors

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7 January 2021

Catalytic Domain of Phosphoinositide-specific Phospholipase C (PLC)

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7 January 2021

Structure, function, and control of phosphoinositide-specific phospholipase C

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7 January 2021