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Growth hormone receptor (Q2299608)

From Wikidata
a protein involved in the binding of the growth hormone
  • growth hormone binding protein
  • somatotropin receptor
  • growth hormone receptor
  • serum binding protein
  • GHR
  • GH receptor
  • growth hormone receptor/binding protein, low molecular weight
  • Growth hormone receptor precursor (GH receptor) (GH binding protein) (GHBP) (Serum binding protein)
  • growth hormone receptor/binding protein, high molecular weight
  • Ghr
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    English
    Growth hormone receptor
    a protein involved in the binding of the growth hormone
    • growth hormone binding protein
    • somatotropin receptor
    • growth hormone receptor
    • serum binding protein
    • GHR
    • GH receptor
    • growth hormone receptor/binding protein, low molecular weight
    • Growth hormone receptor precursor (GH receptor) (GH binding protein) (GHBP) (Serum binding protein)
    • growth hormone receptor/binding protein, high molecular weight
    • Ghr

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    9 references
    retrieved
    8 April 2019
    stated in
    Large-scale structural analysis of the classical human protein tyrosine phosphatome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural Plasticity in a Remodeled Protein-Protein Interface
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16882
    determination method or standard
    IPI
    peptide hormone binding
    determination method or standard
    IBA
    IPI
    5 references
    retrieved
    8 April 2019
    stated in
    Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Growth hormone receptor and serum binding protein: purification, cloning and expression
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Human growth hormone and extracellular domain of its receptor: crystal structure of the complex
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IBA
    cell component
    growth hormone receptor complex
    determination method or standard
    IDA
    4 references
    retrieved
    27 March 2018
    stated in
    Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Human growth hormone and extracellular domain of its receptor: crystal structure of the complex
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P10912&geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    growth hormone receptor complex
    determination method or standard
    IBA
    IDA
    5 references
    retrieved
    8 April 2019
    stated in
    Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Human growth hormone and extracellular domain of its receptor: crystal structure of the complex
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10912
    determination method or standard
    IBA
    biological process
    Gene Atlas image
    PBB GE GHR 205498 at fs.png
    732 × 530; 11 KB
    0 references
    Commons category
    Growth hormone receptor
    0 references

    Identifiers

    Ensembl protein ID
     
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