Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells (Q22007975)

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6 December 2019

title

Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells (English)

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6 December 2019

1

J Sakai

J

Sakai

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6 December 2019

R B Rawson

2

R B

Rawson

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6 December 2019

P J Espenshade

3

P J

Espenshade

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6 December 2019

D Cheng

4

D

Cheng

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6 December 2019

A C Seegmiller

5

A C

Seegmiller

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6 December 2019

J L Goldstein

6

J L

Goldstein

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6 December 2019

M S Brown

7

M S

Brown

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6 December 2019

publication date

1 October 1998

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6 December 2019

language of work or name

0 references

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6 December 2019

volume

2

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6 December 2019

issue

4

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6 December 2019

page(s)

505-514

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Intracellular protein topogenesis

6 December 2019

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Complementation of mutation in acyl-CoA:cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells

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Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.

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Second-site Cleavage in Sterol Regulatory Element-binding Protein Occurs at Transmembrane Junction as Determined by Cysteine Panning

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Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression

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Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

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Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

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Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene

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Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines.

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Complementation Cloning of , a Gene Encoding a Putative Metalloprotease Required for Intramembrane Cleavage of SREBPs

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7 January 2021

Isolation of Cholesterol-requiring Mutant Chinese Hamster Ovary Cells with Defects in Cleavage of Sterol Regulatory Element-binding Proteins at Site 1

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7 January 2021

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7 January 2021

Identification of Complexes between the COOH-terminal Domains of Sterol Regulatory Element-binding Proteins (SREBPs) and SREBP Cleavage-Activating Protein

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7 January 2021

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