SRY (sex determining region Y)-box 4 (Q21984324)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06831

High mobility group box domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q06831

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

1 reference

14 February 2019

transcription coactivator activity

DNA-binding transcription factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Class-C SOX transcription factors control GnRH gene expression via the intronic transcriptional enhancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

DNA-binding transcription activator activity, RNA polymerase II-specific

6 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

transcription cis-regulatory region binding

1 reference

14 February 2019

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

core promoter sequence-specific DNA binding

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

24 April 2018

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

protein heterodimerization activity

1 reference

14 February 2019

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

16 July 2018

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

protein binding

IPI

1 reference

14 February 2019

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

core promoter sequence-specific DNA binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

DNA-binding transcription factor activity, RNA polymerase II-specific

DNA-binding transcription activator activity, RNA polymerase II-specific

8 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

10 September 2018

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

7 November 2018

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

7 references

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

Gene expression profile analysis of mouse colon embryonic development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

8 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Gene expression profile analysis of mouse colon embryonic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

skeletal system development

biological process

1 reference

14 February 2019

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

noradrenergic neuron differentiation

1 reference

14 February 2019

Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

cardiac ventricle formation

1 reference

14 February 2019

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

4 references

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

glial cell development

limb bud formation

1 reference

14 February 2019

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

regulation of protein stability

sympathetic nervous system development

1 reference

14 February 2019

Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

somatic stem cell population maintenance

1 reference

14 February 2019

A functional screen to identify novel effectors of hematopoietic stem cell activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

glucose homeostasis

1 reference

14 February 2019

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

positive regulation of canonical Wnt signaling pathway

1 reference

21 June 2018

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

ventricular septum morphogenesis

1 reference

14 February 2019

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

protein stabilization

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

ascending aorta morphogenesis

1 reference

14 February 2019

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

negative regulation of cell death

mitral valve morphogenesis

1 reference

14 February 2019

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

positive regulation of translation

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

1 reference

16 July 2018

neuroepithelial cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

1 reference

14 February 2019

positive regulation of transcription, DNA-templated

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Class-C SOX transcription factors control GnRH gene expression via the intronic transcriptional enhancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

positive regulation of Wnt signaling pathway

1 reference

21 June 2018

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

negative regulation of protein ubiquitination

development of the heart

1 reference

14 February 2019

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

pro-B cell differentiation

1 reference

14 February 2019

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

atrial septum primum morphogenesis

1 reference

14 February 2019

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

T cell differentiation

1 reference

14 February 2019

Sox-4 facilitates thymocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

kidney morphogenesis

1 reference

14 February 2019

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

positive regulation of cell population proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

spinal cord development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

1 reference

14 February 2019

glial cell proliferation

1 reference

14 February 2019

Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

canonical Wnt signaling pathway

1 reference

21 June 2018

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

positive regulation of N-terminal peptidyl-lysine acetylation

spinal cord motor neuron differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

1 reference

14 February 2019

cardiac right ventricle morphogenesis

1 reference

14 February 2019

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

neural tube formation

1 reference

14 February 2019

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

cellular response to glucose stimulus

1 reference

14 February 2019

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

endocrine pancreas development

1 reference

14 February 2019

The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

negative regulation of cell population proliferation

positive regulation of insulin secretion

1 reference

14 February 2019

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

positive regulation of transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

4 references

16 July 2018

16 July 2018

Cooperative function of POU proteins and SOX proteins in glial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

16 July 2018

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

transcription by RNA polymerase II

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06831&geneProductId=UniProtKB:Q06831

response to hypoxia

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

positive regulation of canonical Wnt signaling pathway

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

cell differentiation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

positive regulation of transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

5 references

14 February 2019

14 February 2019

Cooperative function of POU proteins and SOX proteins in glial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06831

High mobility group box domain

has part(s)

1 reference

InterPro Release 71.0