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CD247 antigen (Q21981009)

From Wikidata

mammalian protein found in Mus musculus

Cd247
T-cell receptor T3 eta chain
T-cell receptor T3 zeta chain
CD3 antigen, zeta polypeptide
CD3-zeta/eta
T-cell surface glycoprotein CD3 zeta chain

Language	Label	Description	Also known as
default for all languages	No label defined
English	CD247 antigen	mammalian protein found in Mus musculus	Cd247 T-cell receptor T3 eta chain T-cell receptor T3 zeta chain CD3 antigen, zeta polypeptide CD3-zeta/eta T-cell surface glycoprotein CD3 zeta chain

Statements

1 reference

25 May 2022

UniProt protein ID

T-cell surface glycoprotein CD3 zeta subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24161

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Phosphorylated immunoreceptor signalling ITAM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method or standard

5 references

9 May 2019

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

9 May 2019

The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

9 May 2019

Lck availability during thymic selection determines the recognition specificity of the T cell repertoire

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

9 May 2019

The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

9 May 2019

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

transmembrane signaling receptor activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

integral component of membrane

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

alpha-beta T cell receptor complex

determination method or standard

T cell receptor complex

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

alpha-beta T cell receptor complex

determination method or standard

3 references

9 May 2019

A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

9 May 2019

Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

biological process

T cell receptor signaling pathway

determination method or standard

1 reference

24 April 2018

Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24161&geneProductId=UniProtKB:P24161

determination method or standard

adaptive immune response

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

immune system process

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

interleukin-2 production

determination method or standard

1 reference

9 May 2019

Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

positive regulation of protein localization to cell surface

determination method or standard

1 reference

9 May 2019

Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24161

determination method or standard

Phosphorylated immunoreceptor signalling ITAM

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24161

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000005907

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000005907

ENSMUSP00000027849

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000027849

ENSMUSP00000083165

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000083165

ENSMUSP00000140926

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000140926

ENSMUSP00000124297

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000124297

ENSMUSP00000124299

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000124299

ENSMUSP00000136456

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000136456

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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