Jump to content

BCL2-like 1 (Q21497061)

From Wikidata
mammalian protein found in Mus musculus
  • Bcl2l1
  • anti-apoptosis regulatory protein
  • apoptosis regulator Bcl-X
  • bcl-2-like protein 1
  • B-cell leukemia/lymphoma x
edit
Language Label Description Also known as
default for all languages
No label defined
    English
    BCL2-like 1
    mammalian protein found in Mus musculus
    • Bcl2l1
    • anti-apoptosis regulatory protein
    • apoptosis regulator Bcl-X
    • bcl-2-like protein 1
    • B-cell leukemia/lymphoma x

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    8 references
    retrieved
    14 February 2019
    stated in
    Phosphorylation of Bcl-associated death protein (Bad) by erythropoietin-activated c-Jun N-terminal protein kinase 1 contributes to survival of erythropoietin-dependent cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q64373
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Dual role of proapoptotic BAD in insulin secretion and beta cell survival
    GOA
    curator
    UniProt
    UniProt protein ID
    Q64373
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q64373
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Bcl-2 family interaction with the mitochondrial morphogenesis machinery
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    PUMA couples the nuclear and cytoplasmic proapoptotic function of p53
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IPI
    cell component
    mitochondrion
    determination method or standard
    IDA
    IEA
    ISO
    7 references
    retrieved
    31 January 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    ISO
    retrieved
    31 January 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q64373
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IEA
    retrieved
    31 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IEA
    retrieved
    31 January 2018
    stated in
    Bcl-2 family interaction with the mitochondrial morphogenesis machinery
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    31 January 2018
    stated in
    bcl-xLx is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    31 January 2018
    stated in
    BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    31 January 2018
    stated in
    Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    mitochondrion
    determination method or standard
    HDA
    IDA
    IEA
    ISO
    7 references
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    ISO
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q64373
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IEA
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IEA
    retrieved
    14 February 2019
    stated in
    BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    bcl-xLx is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Bcl-2 family interaction with the mitochondrial morphogenesis machinery
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    HDA
    biological process
    negative regulation of neuron apoptotic process
    determination method or standard
    IDA
    IGI
    IMP
    6 references
    retrieved
    14 February 2019
    stated in
    Bcl-X(L)-caspase-9 interactions in the developing nervous system: evidence for multiple death pathways
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IMP
    retrieved
    14 February 2019
    stated in
    Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IGI
    retrieved
    14 February 2019
    stated in
    Bcl-X(L)-caspase-9 interactions in the developing nervous system: evidence for multiple death pathways
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IGI
    retrieved
    14 February 2019
    stated in
    BAD is a pro-survival factor prior to activation of its pro-apoptotic function
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Bax promotes neuronal survival and antagonises the survival effects of neurotrophic factors
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    negative regulation of apoptotic process
    determination method or standard
    IDA
    IGI
    IEA
    IMP
    ISO
    10 references
    retrieved
    31 January 2018
    stated in
    Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    ISO
    retrieved
    31 January 2018
    stated in
    Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IMP
    retrieved
    31 January 2018
    stated in
    c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IMP
    retrieved
    31 January 2018
    stated in
    Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IGI
    retrieved
    31 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IEA
    retrieved
    31 January 2018
    stated in
    Identification of a Novel Phosphorylation Site, Ser-170, as a Regulator of Bad Pro-apoptotic Activity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    31 January 2018
    stated in
    bcl-xLx is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    31 January 2018
    stated in
    Bax and Bcl-xs are induced at the onset of apoptosis in involuting mammary epithelial cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    31 January 2018
    stated in
    Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    31 January 2018
    stated in
    Regulation of the lifespan in dendritic cell subsets
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64373&geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    negative regulation of apoptotic process
    determination method or standard
    IBA
    IDA
    IEA
    IGI
    IMP
    ISO
    9 references
    retrieved
    14 February 2019
    stated in
    Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    ISO
    retrieved
    14 February 2019
    stated in
    Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IMP
    retrieved
    14 February 2019
    stated in
    c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IMP
    retrieved
    14 February 2019
    stated in
    Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IGI
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IEA
    retrieved
    14 February 2019
    stated in
    Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Regulation of the lifespan in dendritic cell subsets
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Identification of a Novel Phosphorylation Site, Ser-170, as a Regulator of Bad Pro-apoptotic Activity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64373
    determination method or standard
    IBA

    Identifiers

    PDB structure ID
     
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    edit
                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q21497061&oldid=2023155768"