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DEAD-box helicase 5 (Q21170314)

From Wikidata
mammalian protein found in Homo sapiens
  • DEAD box-5
  • DDX5
  • probable ATP-dependent RNA helicase DDX5
  • DEAD box protein 5
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 5
  • ATP-dependent RNA helicase DDX5
  • RNA helicase p68
  • Ddx5 protein, human
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    English
    DEAD-box helicase 5
    mammalian protein found in Homo sapiens
    • DEAD box-5
    • DDX5
    • probable ATP-dependent RNA helicase DDX5
    • DEAD box protein 5
    • DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
    • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD)
    • DEAD (Asp-Glu-Ala-Asp) box helicase 5
    • ATP-dependent RNA helicase DDX5
    • RNA helicase p68
    • Ddx5 protein, human

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    31 references
    retrieved
    8 April 2019
    stated in
    Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.
    GOA
    curator
    UniProt
    UniProt protein ID
    P17844
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA
    GOA
    curator
    UniProt
    UniProt protein ID
    P17844
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site
    GOA
    curator
    UniProt
    UniProt protein ID
    P17844
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P17844
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation
    GOA
    curator
    UniProt
    UniProt protein ID
    P17844
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The nuclear DEAD box RNA helicase p68 interacts with the nucleolar protein fibrillarin and colocalizes specifically in nascent nucleoli during telophase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Dynamic protein-protein interaction wiring of the human spliceosome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A physical interaction network of dengue virus and human proteins
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Modulation of microRNA processing by p53
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SMAD proteins control DROSHA-mediated microRNA maturation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylated p68 RNA helicase activates snail1 transcription by promoting HDAC1 dissociation from the snail1 promoter
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The variable N-terminal region of DDX5 contains structural elements and auto-inhibits its interaction with NS5B of hepatitis C virus
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cellular RNA helicase p68 relocalization and interaction with the hepatitis C virus (HCV) NS5B protein and the potential role of p68 in HCV RNA replication
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    DDX5 Facilitates HIV-1 Replication as a Cellular Co-Factor of Rev
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SMAD proteins control DROSHA-mediated microRNA maturation
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex
    GOA
    curator
    AgBase
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein
    GOA
    curator
    AgBase
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844
    determination method or standard
    IPI
    cell component
    biological process

    Identifiers

    MeSH descriptor ID
    C506749
    subject named as
    Ddx5 protein, human
    0 references
    Ensembl protein ID
     
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