CEA cell adhesion molecule 5 (Q21132936)

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mammalian protein found in Homo sapiens

carcinoembryonic antigen-related cell adhesion molecule 5
meconium antigen 100
CEACAM5
Carcinoembryonic antigen
carcinoembryonic antigen related cell adhesion molecule 5
CEA
CD66e

Language	Label	Description	Also known as
English	CEA cell adhesion molecule 5	mammalian protein found in Homo sapiens	carcinoembryonic antigen-related cell adhesion molecule 5 meconium antigen 100 CEACAM5 Carcinoembryonic antigen carcinoembryonic antigen related cell adhesion molecule 5 CEA CD66e

Statements

1 reference

13 November 2019

UniProt protein ID

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P06731

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P06731

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin V-set domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

GPI anchor binding

determination method

1 reference

8 April 2019

The specificity for the differentiation blocking activity of carcinoembryonic antigen resides in its glycophosphatidyl-inositol anchor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

identical protein binding

determination method

identical protein binding

determination method

3 references

8 April 2019

Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

8 April 2019

Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

8 April 2019

Diverse oligomeric states of CEACAM IgV domains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

anchored component of membrane

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06731&geneProductId=UniProtKB:P06731

determination method

basolateral plasma membrane

determination method

1 reference

8 April 2019

Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

integral component of plasma membrane

determination method

extracellular exosome

determination method

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06731&geneProductId=UniProtKB:P06731

determination method

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06731&geneProductId=UniProtKB:P06731

determination method

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06731&geneProductId=UniProtKB:P06731

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

integral component of external side of plasma membrane

determination method

1 reference

8 April 2019

Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

extracellular region

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

8 April 2019

Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

8 April 2019

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

anchored component of membrane

determination method

biological process

homotypic cell-cell adhesion

determination method

1 reference

8 April 2019

Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

negative regulation of apoptotic process

determination method

1 reference

8 April 2019

Controlled ribozyme targeting demonstrates an antiapoptotic effect of carcinoembryonic antigen in HT29 colon cancer cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

negative regulation of anoikis

determination method

1 reference

8 April 2019

Human carcinoembryonic antigen functions as a general inhibitor of anoikis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

negative regulation of myotube differentiation

determination method

C-terminal protein lipidation

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P06731&geneProductId=UniProtKB:P06731

determination method

leukocyte migration

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

apoptotic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

homophilic cell adhesion via plasma membrane adhesion molecules

determination method

1 reference

8 April 2019

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

determination method

1 reference

8 April 2019

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06731

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000221992

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000221992

ENSP00000381600

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000381600

ENSP00000385072

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000385072

ENSP00000468997

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000468997

ENSP00000473252

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000473252

ENSP00000480800

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000480800

ENSP00000482157

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482157

ENSP00000482303

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482303

0 references

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

Wikipedia(5 entries)

dewiki CD66e
enwiki CEACAM5
ruwiki CEACAM5
ttwiki CEACAM5
ukwiki CEACAM5

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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