Siah E3 ubiquitin protein ligase 2 (Q21123631)

E3 ubiquitin-protein ligase SIN-like

1 reference

Zinc finger, RING/FYVE/PHD-type

1 reference

Seven-in-absentia protein, TRAF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, SIAH-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

transcription corepressor activity

1 reference

8 April 2019

hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

5 references

8 April 2019

USP13 enzyme regulates Siah2 ligase stability and activity via noncatalytic ubiquitin-binding domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

MOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screens

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

ubiquitin conjugating enzyme binding

IPI

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

ubiquitin-protein transferase activity

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

1 January 2018

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

ubiquitin protein ligase activity

EXP

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

ubiquitin protein ligase activity

IBA

3 references

ubiquitin-protein transferase activity

3 references

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

2 references

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

small GTPase mediated signal transduction

IMP

1 reference

8 April 2019

hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

regulation of protein ubiquitination

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

negative regulation of extrinsic apoptotic signaling pathway

1 reference

8 April 2019

Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

negative regulation of apoptotic process

IMP

1 reference

8 April 2019

Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

protein ubiquitination

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

negative regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

negative regulation of nucleic acid-templated transcription

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

protein polyubiquitination

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

protein deubiquitination

1 reference

8 April 2019

ubiquitin-dependent protein catabolic process

4 references

21 June 2018

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

negative regulation of netrin-activated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

ubiquitin-dependent protein catabolic process

5 references

10 September 2018

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43255&geneProductId=UniProtKB:O43255

proteasome-mediated ubiquitin-dependent protein catabolic process

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

ubiquitin-dependent protein catabolic process

IBA

6 references

8 April 2019

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43255

has part(s)

Zinc finger, RING-type

1 reference

Zinc finger, SIAH-type

1 reference

Seven-in-absentia protein, TRAF-like domain

1 reference