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Regulator of chromosome condensation 1 (Q21117726)

From Wikidata

mammalian protein found in Homo sapiens

SNHG3-RCC1 readthrough
regulator of chromosome condensation
Chromosome condensation protein 1
cell cycle regulatory protein
guanine nucleotide-releasing protein
RCC1

Language	Label	Description	Also known as
default for all languages	No label defined
English	Regulator of chromosome condensation 1	mammalian protein found in Homo sapiens	SNHG3-RCC1 readthrough regulator of chromosome condensation Chromosome condensation protein 1 cell cycle regulatory protein guanine nucleotide-releasing protein RCC1

Statements

1 reference

13 November 2019

UniProt protein ID

Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P18754

Regulator of chromosome condensation, RCC1, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

guanyl-nucleotide exchange factor activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

histone binding

determination method or standard

1 reference

8 April 2019

Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

chromatin binding

determination method or standard

1 reference

8 April 2019

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

protein binding

determination method or standard

12 references

8 April 2019

Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Novel function of beta-arrestin2 in the nucleus of mature spermatozoa

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Structure of RCC1 chromatin factor bound to the nucleosome core particle

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Human RanBP3, a group of nuclear RanGTP binding proteins1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

nucleosomal DNA binding

determination method or standard

1 reference

8 April 2019

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

nucleosome binding

determination method or standard

1 reference

8 April 2019

RCC1 Uses a Conformationally Diverse Loop Region to Interact with the Nucleosome: A Model for the RCC1–Nucleosome Complex

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

sulfate binding

determination method or standard

1 reference

8 April 2019

Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

protein heterodimerization activity

determination method or standard

1 reference

8 April 2019

Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

nuclear membrane

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

condensed nuclear chromosome

determination method or standard

1 reference

8 April 2019

Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

3 references

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18754&geneProductId=UniProtKB:P18754

determination method or standard

31 October 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18754&geneProductId=UniProtKB:P18754

determination method or standard

31 October 2017

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18754&geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

1 reference

8 April 2019

Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

protein-containing complex

determination method or standard

1 reference

8 April 2019

Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

biological process

chromosome segregation

determination method or standard

1 reference

8 April 2019

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

1 reference

31 October 2017

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18754&geneProductId=UniProtKB:P18754

determination method or standard

mitotic spindle organization

determination method or standard

1 reference

8 April 2019

Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

spindle assembly

determination method or standard

1 reference

8 April 2019

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

regulation of mitotic nuclear division

determination method or standard

1 reference

8 April 2019

Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

protein heterotetramerization

determination method or standard

1 reference

8 April 2019

Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

regulation of molecular function

determination method or standard

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18754&geneProductId=UniProtKB:P18754

determination method or standard

G1/S transition of mitotic cell cycle

determination method or standard

1 reference

8 April 2019

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18754

determination method or standard

Regulator of chromosome condensation, RCC1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P18754

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000362937

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000362937

ENSP00000362938

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000362938

ENSP00000362939

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000362939

ENSP00000381931

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000381931

ENSP00000394650

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394650

ENSP00000402260

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000402260

ENSP00000402740

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000402740

ENSP00000405258

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000405258

ENSP00000413644

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000413644

ENSP00000472057

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472057

ENSP00000497402

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000497402

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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