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RAD9 checkpoint clamp component A (Q21116022)

From Wikidata

mammalian protein found in Homo sapiens

RAD9A
cell cycle checkpoint control protein RAD9A
RAD9 homolog A
DNA repair exonuclease rad9 homolog A
hRAD9

Language	Label	Description	Also known as
default for all languages	No label defined
English	RAD9 checkpoint clamp component A	mammalian protein found in Homo sapiens	RAD9A cell cycle checkpoint control protein RAD9A RAD9 homolog A DNA repair exonuclease rad9 homolog A hRAD9

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99638

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

SH3 domain binding

determination method or standard

1 reference

8 April 2019

c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

histone deacetylase binding

determination method or standard

1 reference

8 April 2019

HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

exodeoxyribonuclease III activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

protein binding

determination method or standard

9 references

8 April 2019

Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

Crystal structure of the human rad9-hus1-rad1 clamp

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

3'-5' exonuclease activity

determination method or standard

1 reference

24 April 2018

Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonuclease

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99638&geneProductId=UniProtKB:Q99638

determination method or standard

determination method or standard

1 reference

8 April 2019

The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

nuclease activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

exonuclease activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

hydrolase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

protein kinase binding

determination method or standard

1 reference

8 April 2019

Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

biological process

cell cycle checkpoint signaling

determination method or standard

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99638&geneProductId=UniProtKB:Q99638

determination method or standard

DNA damage checkpoint signaling

determination method or standard

3 references

8 April 2019

A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

DNA replication checkpoint signaling

determination method or standard

1 reference

8 April 2019

A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

cellular response to ionizing radiation

determination method or standard

1 reference

24 April 2018

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99638&geneProductId=UniProtKB:Q99638

determination method or standard

nucleic acid phosphodiester bond hydrolysis

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

determination method or standard

3 references

24 April 2018

A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99638&geneProductId=UniProtKB:Q99638

determination method or standard

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99638&geneProductId=UniProtKB:Q99638

determination method or standard

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99638&geneProductId=UniProtKB:Q99638

determination method or standard

cellular response to ionizing radiation

determination method or standard

DNA replication

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

regulation of signal transduction by p53 class mediator

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99638

determination method or standard

EC enzyme number

3.1.11.2

1 reference

UniProt protein ID

23 July 2026

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000311360

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000311360

ENSP00000442064

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000442064

ENSP00000444979

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000444979

ENSP00000445137

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000445137

ENSP00000478994

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000478994

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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