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Signal-induced proliferation-associated 1 (Q21114053)

From Wikidata

mammalian protein found in Homo sapiens

signal-induced proliferation-associated gene 1
GTPase-activating protein Spa-1
signal-induced proliferation-associated protein 1
SIPA1
p130 SPA-1
sipa-1

Language	Label	Description	Also known as
default for all languages	No label defined
English	Signal-induced proliferation-associated 1	mammalian protein found in Homo sapiens	signal-induced proliferation-associated gene 1 GTPase-activating protein Spa-1 signal-induced proliferation-associated protein 1 SIPA1 p130 SPA-1 sipa-1

Statements

1 reference

13 November 2019

UniProt protein ID

Rap/Ran-GAP superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96FS4

PDZ superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96FS4

Rap GTPase activating protein domain family

1 reference

based on heuristic

inferred from protein domain or family

PDZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method or standard

1 reference

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

GTPase activator activity

determination method or standard

5 references

7 November 2018

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96FS4&geneProductId=UniProtKB:Q96FS4

determination method or standard

7 November 2018

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96FS4&geneProductId=UniProtKB:Q96FS4

determination method or standard

7 November 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96FS4&geneProductId=UniProtKB:Q96FS4

determination method or standard

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96FS4&geneProductId=UniProtKB:Q96FS4

determination method or standard

7 November 2018

Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96FS4&geneProductId=UniProtKB:Q96FS4

determination method or standard

protein C-terminus binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

GTPase activator activity

determination method or standard

4 references

1 January 2018

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

1 January 2018

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

GTPase activator activity

determination method or standard

3 references

8 April 2019

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

perinuclear region of cytoplasm

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

transport vesicle

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

endomembrane system

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

protein-containing complex

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

biological process

negative regulation of cell adhesion

determination method or standard

1 reference

8 April 2019

Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

negative regulation of cell cycle

determination method or standard

1 reference

8 April 2019

Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

cellular response to water deprivation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

cell population proliferation

determination method or standard

1 reference

1 January 2018

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

intracellular signal transduction

determination method or standard

1 reference

8 April 2019

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

regulation of small GTPase mediated signal transduction

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

cytoskeleton organization

determination method or standard

1 reference

8 April 2019

SPAL, a Rap-specific GTPase activating protein, is present in the NMDA receptor-PSD-95 complex in the hippocampus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

negative regulation of cell growth

determination method or standard

1 reference

8 April 2019

Regulatory mechanisms of lymphocyte proliferation: roles of Spa-1 gene

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

signal transduction

determination method or standard

1 reference

8 April 2019

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

positive regulation of GTPase activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96FS4

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96FS4

Rap GTPase activating protein domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96FS4

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000377771

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377771

ENSP00000436269

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436269

ENSP00000433686

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433686

ENSP00000434362

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434362

ENSP00000436683

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436683

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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