Jump to content

SMAD specific E3 ubiquitin protein ligase 2 (Q21112471)

From Wikidata
mammalian protein found in Homo sapiens
  • E3 ubiquitin-protein ligase SMURF2
  • SMAD-specific E3 ubiquitin-protein ligase 2
  • HECT-type E3 ubiquitin transferase SMURF2
  • hSMURF2
  • E3 ubiquitin ligase SMURF2
  • SMURF2
  • SMAD ubiquitination regulatory factor 2
edit
Language Label Description Also known as
default for all languages
No label defined
    English
    SMAD specific E3 ubiquitin protein ligase 2
    mammalian protein found in Homo sapiens
    • E3 ubiquitin-protein ligase SMURF2
    • SMAD-specific E3 ubiquitin-protein ligase 2
    • HECT-type E3 ubiquitin transferase SMURF2
    • hSMURF2
    • E3 ubiquitin ligase SMURF2
    • SMURF2
    • SMAD ubiquitination regulatory factor 2

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    11 references
    retrieved
    8 April 2019
    stated in
    SCFFBXL15regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1
    GOA
    curator
    UniProt
    UniProt protein ID
    Q9HAU4
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Hepatitis C virus infection protein network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Functional proteomics mapping of a human signaling pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SCFFBXL15regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAU4
    determination method or standard
    IPI
    cell component
    biological process

    Identifiers

    Freebase ID
    /m/02kg971
    0 references
     
    edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21112471&oldid=2022949787"