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Ubiquitin conjugating enzyme E2 D3 (Q21112096)

From Wikidata
mammalian protein found in Homo sapiens
  • UBE2D3
  • ubiquitin-conjugating enzyme E2 D3
  • ubiquitin-protein ligase D3
  • (E3-independent) E2 ubiquitin-conjugating enzyme D3
  • ubiquitin-conjugating enzyme E2-17 kDa 3
  • ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5)
  • 2.3.2.24
  • ubiquitin carrier protein D3
  • ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
  • E2 ubiquitin-conjugating enzyme D3
  • ubiquitin conjugating enzyme E2D 3
  • ubiquitin-conjugating enzyme E2(17)KB 3
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    English
    Ubiquitin conjugating enzyme E2 D3
    mammalian protein found in Homo sapiens
    • UBE2D3
    • ubiquitin-conjugating enzyme E2 D3
    • ubiquitin-protein ligase D3
    • (E3-independent) E2 ubiquitin-conjugating enzyme D3
    • ubiquitin-conjugating enzyme E2-17 kDa 3
    • ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5)
    • 2.3.2.24
    • ubiquitin carrier protein D3
    • ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
    • E2 ubiquitin-conjugating enzyme D3
    • ubiquitin conjugating enzyme E2D 3
    • ubiquitin-conjugating enzyme E2(17)KB 3

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    13 references
    retrieved
    31 October 2017
    stated in
    The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes
    GOA
    curator
    UniProt
    UniProt protein ID
    P61077
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Physical and functional interactions between ZIP kinase and UbcH5
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Towards a proteome-scale map of the human protein–protein interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IPI
    ubiquitin conjugating enzyme activity
    determination method or standard
    IDA
    5 references
    retrieved
    31 October 2017
    stated in
    Bifunctional Apoptosis Regulator (BAR), an Endoplasmic Reticulum (ER)-associated E3 Ubiquitin Ligase, Modulates BI-1 Protein Stability and Function in ER Stress
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    Structural and functional characterization of the monomeric U-box domain from E4B
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    ubiquitin-protein transferase activity
    determination method or standard
    IDA
    TAS
    7 references
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    TAS
    retrieved
    31 October 2017
    stated in
    Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53
    GOA
    curator
    Proteome Inc.
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    TAS
    retrieved
    31 October 2017
    stated in
    Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis
    GOA
    curator
    UniProt
    UniProt protein ID
    P61077
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
    GOA
    curator
    UniProt
    UniProt protein ID
    P61077
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis
    GOA
    curator
    UniProt
    UniProt protein ID
    P61077
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    Priming and Extending: A UbcH5/Cdc34 E2 Handoff Mechanism for Polyubiquitination on a SCF Substrate
    GOA
    curator
    UniProt
    UniProt protein ID
    P61077
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
    GOA
    curator
    UniProt
    UniProt protein ID
    P61077
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077
    determination method or standard
    IDA
    cell component
    biological process

    Identifiers

    Ensembl protein ID
     
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                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q21112096&oldid=2022948156"