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Baculoviral IAP repeat containing 2 (Q21111704)

From Wikidata
mammalian protein found in Homo sapiens
  • BIRC2
  • RING-type E3 ubiquitin transferase BIRC2
  • hIAP2
  • C-IAP1
  • inhibitor of apoptosis protein 2
  • cellular inhibitor of apoptosis 1
  • baculoviral IAP repeat-containing protein 2
  • TNFR2-TRAF-signaling complex protein 2
  • IAP-2
  • RING finger protein 48
  • hIAP-2
  • NFR2-TRAF signalling complex protein
  • IAP homolog B
  • apoptosis inhibitor 1
  • Cellular Inhibitor of Apoptosis Protein 1
  • CIAP1
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    English
    Baculoviral IAP repeat containing 2
    mammalian protein found in Homo sapiens
    • BIRC2
    • RING-type E3 ubiquitin transferase BIRC2
    • hIAP2
    • C-IAP1
    • inhibitor of apoptosis protein 2
    • cellular inhibitor of apoptosis 1
    • baculoviral IAP repeat-containing protein 2
    • TNFR2-TRAF-signaling complex protein 2
    • IAP-2
    • RING finger protein 48
    • hIAP-2
    • NFR2-TRAF signalling complex protein
    • IAP homolog B
    • apoptosis inhibitor 1
    • Cellular Inhibitor of Apoptosis Protein 1
    • CIAP1

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    22 references
    retrieved
    9 May 2019
    stated in
    Asymmetric recruitment of cIAPs by TRAF2
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    cIAP1 Localizes to the nuclear compartment and modulates the cell cycle
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    The USP19 Deubiquitinase Regulates the Stability of c-IAP1 and c-IAP2
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Widespread macromolecular interaction perturbations in human genetic disorders
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Toward an understanding of the protein interaction network of the human liver
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Towards a proteome-scale map of the human protein–protein interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Network organization of the human autophagy system
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    OTUB1 modulates c-IAP1 stability to regulate signalling pathways
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Next-generation sequencing to generate interactome datasets
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    retrieved
    9 May 2019
    stated in
    A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IPI
    cell component
    nucleus
    determination method or standard
    IBA
    IDA
    IEA
    6 references
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    cIAP1 Localizes to the nuclear compartment and modulates the cell cycle
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13490
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13490
    determination method or standard
    IBA
    biological process
    Commons category
    Cellular Inhibitor of Apoptosis Protein 1
    0 references

    Identifiers

    PDB structure ID
     
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