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transcription factor 3 (Q21111604)

From Wikidata
mammalian protein found in Homo sapiens
  • negative vitamin D response element-binding protein
  • Immunoglobulin enhancer-binding factor E12/E47
  • TCF3
  • bHLHb21
  • transcription factor ITF-1
  • VDR interacting repressor
  • immunoglobulin transcription factor 1
  • transcription factor E2-alpha
  • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
  • helix-loop-helix protein HE47
  • vitamin D receptor-interacting repressor
  • kappa-E2-binding factor
  • NOL1-TCF3 fusion
  • class B basic helix-loop-helix protein 21
  • TCF-3
  • transcription factor 3 variant 3
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    English
    transcription factor 3
    mammalian protein found in Homo sapiens
    • negative vitamin D response element-binding protein
    • Immunoglobulin enhancer-binding factor E12/E47
    • TCF3
    • bHLHb21
    • transcription factor ITF-1
    • VDR interacting repressor
    • immunoglobulin transcription factor 1
    • transcription factor E2-alpha
    • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
    • helix-loop-helix protein HE47
    • vitamin D receptor-interacting repressor
    • kappa-E2-binding factor
    • NOL1-TCF3 fusion
    • class B basic helix-loop-helix protein 21
    • TCF-3
    • transcription factor 3 variant 3

    Statements

    molecular function
    DNA-binding transcription factor activity
    determination method or standard
    NAS
    IDA
    6 references
    retrieved
    27 March 2018
    stated in
    A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    NAS
    retrieved
    27 March 2018
    stated in
    Regulation of E2A activities by histone acetyltransferases in B lymphocyte development
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Promotion of cell cycle progression by basic helix-loop-helix E2A
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    protein binding
    determination method or standard
    IPI
    10 references
    retrieved
    8 April 2019
    stated in
    Notch signaling induces rapid degradation of achaete-scute homolog 1.
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mutations affecting the BHLHA9 DNA-binding domain cause MSSD, mesoaxial synostotic syndactyly with phalangeal reduction, Malik-Percin type
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HEB and E2A function as SMAD/FOXH1 cofactors
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SCL binds the human homologue of DRG in vivo
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    protein heterodimerization activity
    determination method or standard
    NAS
    IDA
    IPI
    5 references
    retrieved
    27 March 2018
    stated in
    Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    NAS
    retrieved
    27 March 2018
    stated in
    Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    27 March 2018
    stated in
    Regulation of scleraxis function by interaction with the bHLH protein E47
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    protein heterodimerization activity
    determination method or standard
    IBA
    IDA
    IPI
    NAS
    6 references
    retrieved
    8 April 2019
    stated in
    Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    NAS
    retrieved
    8 April 2019
    stated in
    Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of scleraxis function by interaction with the bHLH protein E47
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IBA
    cell component
    nucleus
    determination method or standard
    NAS
    IDA
    IEA
    8 references
    retrieved
    27 March 2018
    stated in
    A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    NAS
    retrieved
    27 March 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IEA
    retrieved
    27 March 2018
    stated in
    Regulation of scleraxis function by interaction with the bHLH protein E47
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Regulation of E2A activities by histone acetyltransferases in B lymphocyte development
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    GOA
    curator
    Human Protein Atlas
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Saethre-Chotzen mutations cause TWIST protein degradation or impaired nuclear location
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    HEB and E2A function as SMAD/FOXH1 cofactors
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    nucleus
    determination method or standard
    IBA
    IDA
    IEA
    NAS
    7 references
    retrieved
    8 April 2019
    stated in
    A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    NAS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Regulation of scleraxis function by interaction with the bHLH protein E47
    GOA
    curator
    UniProt
    UniProt protein ID
    P15923
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Human Protein Atlas
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    HEB and E2A function as SMAD/FOXH1 cofactors
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923
    determination method or standard
    IBA
    biological process

    Identifiers

    MeSH descriptor ID
    D058127
    subject named as
    Transcription Factor 3
    0 references
    RefSeq protein ID
    Ensembl protein ID
     
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