RUNX1 partner transcriptional co-repressor 1 (Q21108964)

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mammalian protein found in Homo sapiens
  • eight twenty one protein
  • zinc finger MYND domain-containing protein 2
  • runt related transcription factor 1; translocated to, 1 (cyclin D related)
  • acute myelogenous leukemia 1 translocation 1, cyclin-D related
  • protein CBFA2T1
  • RUNX1 translocation partner 1
  • Protein MTG8
  • Cyclin-D-related protein
  • RUNX1T1
  • Protein ETO
  • core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related
  • myeloid translocation gene on 8q22
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Language Label Description Also known as
English
RUNX1 partner transcriptional co-repressor 1
mammalian protein found in Homo sapiens
  • eight twenty one protein
  • zinc finger MYND domain-containing protein 2
  • runt related transcription factor 1; translocated to, 1 (cyclin D related)
  • acute myelogenous leukemia 1 translocation 1, cyclin-D related
  • protein CBFA2T1
  • RUNX1 translocation partner 1
  • Protein MTG8
  • Cyclin-D-related protein
  • RUNX1T1
  • Protein ETO
  • core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related
  • myeloid translocation gene on 8q22

Statements

molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription
GOA
curator
UniProt
UniProt protein ID
Q06455
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06455
determination method
IPI
retrieved
8 April 2019
stated in
Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism
GOA
curator
UniProt
UniProt protein ID
Q06455
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06455
determination method
IPI
retrieved
8 April 2019
stated in
A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06455
determination method
IPI
retrieved
8 April 2019
stated in
Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06455
determination method
IPI
retrieved
8 April 2019
stated in
AML1-ETO interacts with Sp1 and antagonizes Sp1 transactivity through RUNT domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06455
determination method
IPI
biological process

Identifiers

RefSeq protein ID
Ensembl protein ID
 
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