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Platelet derived growth factor receptor alpha (Q21102511)

From Wikidata
mammalian protein found in Homo sapiens
  • CD140a antigen
  • Alpha platelet-derived growth factor receptor
  • PDGFRA
  • platelet-derived growth factor receptor, alpha polypeptide
  • CD140 antigen-like family member A
  • platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor alpha receptor
  • PDGFR-2
  • alpha-type platelet-derived growth factor receptor
  • PDGF-R-alpha
  • platelet-derived growth factor receptor 2
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    English
    Platelet derived growth factor receptor alpha
    mammalian protein found in Homo sapiens
    • CD140a antigen
    • Alpha platelet-derived growth factor receptor
    • PDGFRA
    • platelet-derived growth factor receptor, alpha polypeptide
    • CD140 antigen-like family member A
    • platelet-derived growth factor receptor alpha
    • Platelet-derived growth factor alpha receptor
    • PDGFR-2
    • alpha-type platelet-derived growth factor receptor
    • PDGF-R-alpha
    • platelet-derived growth factor receptor 2

    Statements

    part of
    molecular function
    protein binding
    determination method or standard
    IPI
    8 references
    retrieved
    8 April 2019
    stated in
    Vascular endothelial growth factor can signal through platelet-derived growth factor receptors
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Differential interaction of CrkII adaptor protein with platelet-derived growth factor alpha- and beta-receptors is determined by its internal tyrosine phosphorylation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    platelet-derived growth factor alpha-receptor activity
    determination method or standard
    IDA
    IEA
    IMP
    6 references
    retrieved
    31 October 2017
    stated in
    Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IMP
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IEA
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IEA
    retrieved
    31 October 2017
    stated in
    Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    platelet-derived growth factor binding
    determination method or standard
    IDA
    IEA
    IPI
    5 references
    retrieved
    31 October 2017
    stated in
    Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IEA
    retrieved
    31 October 2017
    stated in
    Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P16234&geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    platelet-derived growth factor alpha-receptor activity
    determination method or standard
    IBA
    IDA
    IEA
    IMP
    7 references
    retrieved
    8 April 2019
    stated in
    Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IBA
    platelet-derived growth factor binding
    determination method or standard
    IBA
    IDA
    IEA
    IPI
    6 references
    retrieved
    8 April 2019
    stated in
    PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    P16234
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16234
    determination method or standard
    IBA
    cell component
    biological process

    Identifiers

     
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