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Tripartite motif containing 28 (Q21102214)

From Wikidata
mammalian protein found in Homo sapiens
  • TIF1-beta
  • KRIP-1
  • protein phosphatase 1, regulatory subunit 157
  • KRAB-associated protein 1
  • KAP-1
  • TRIM28
  • RING-type E3 ubiquitin transferase TIF1-beta
  • E3 SUMO-protein ligase TRIM28
  • Tripartite motif-containing protein 28
  • RING finger protein 96
  • 6.3.2.-
  • nuclear corepressor KAP-1
  • transcriptional intermediary factor 1-beta
  • transcription intermediary factor 1-beta
  • KRAB [Kruppel-associated box domain]-associated protein 1
  • KRAB-interacting protein 1
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    English
    Tripartite motif containing 28
    mammalian protein found in Homo sapiens
    • TIF1-beta
    • KRIP-1
    • protein phosphatase 1, regulatory subunit 157
    • KRAB-associated protein 1
    • KAP-1
    • TRIM28
    • RING-type E3 ubiquitin transferase TIF1-beta
    • E3 SUMO-protein ligase TRIM28
    • Tripartite motif-containing protein 28
    • RING finger protein 96
    • 6.3.2.-
    • nuclear corepressor KAP-1
    • transcriptional intermediary factor 1-beta
    • transcription intermediary factor 1-beta
    • KRAB [Kruppel-associated box domain]-associated protein 1
    • KRAB-interacting protein 1

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    26 references
    retrieved
    8 April 2019
    stated in
    ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The novel protein complex with SMARCAD1/KIAA1122 binds to the vicinity of TSS
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of E2F1 function by the nuclear corepressor KAP1
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Interactions of ErbB4 and Kap1 Connect the Growth Factor and DNA Damage Response Pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A human protein-protein interaction network: a resource for annotating the proteome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of novel small molecules that inhibit protein-protein interactions between MAGE and KAP-1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A High-Density Map for Navigating the Human Polycomb Complexome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Analysis of the human HP1 interactome reveals novel binding partners
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A human interactome in three quantitative dimensions organized by stoichiometries and abundances
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A human MAP kinase interactome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IPI
    cell component
    nucleus
    determination method or standard
    IBA
    IDA
    IEA
    ISS
    6 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    KAP-1, a novel corepressor for the highly conserved KRAB repression domain
    GOA
    curator
    UniProt
    UniProt protein ID
    Q13263
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13263
    determination method or standard
    IBA
    biological process

    Identifiers

    MeSH descriptor ID
    D000076183
    subject named as
    Tripartite Motif-Containing Protein 28
    0 references
     
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