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YES proto-oncogene 1, Src family tyrosine kinase (Q21097216)

From Wikidata
mammalian protein found in Homo sapiens
  • proto-oncogene tyrosine-protein kinase YES
  • YES1 proto-oncogene, Src family tyrosine kinase
  • YES1
  • v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
  • cellular yes-1 protein
  • Yamaguchi sarcoma oncogene
  • proto-oncogene c-Yes
  • tyrosine-protein kinase Yes
  • p61-Yes
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    English
    YES proto-oncogene 1, Src family tyrosine kinase
    mammalian protein found in Homo sapiens
    • proto-oncogene tyrosine-protein kinase YES
    • YES1 proto-oncogene, Src family tyrosine kinase
    • YES1
    • v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
    • cellular yes-1 protein
    • Yamaguchi sarcoma oncogene
    • proto-oncogene c-Yes
    • tyrosine-protein kinase Yes
    • p61-Yes

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    10 references
    retrieved
    8 April 2019
    stated in
    Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phospho-tyrosine dependent protein-protein interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    EG-1 interacts with c-Src and activates its signaling pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IPI
    protein tyrosine kinase activity
    determination method or standard
    EXP
    TAS
    IEA
    10 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Characterization of cDNA clones for the human c-yes gene
    GOA
    curator
    Proteome Inc.
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P07947
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Vav2 is required for cell spreading
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07947
    determination method or standard
    EXP
    cell component
    biological process

    Identifiers

     
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