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Aquaporin 1 (Q2083074)

From Wikidata
mammalian protein found in Homo sapiens
  • AQP1
  • aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group)
  • channel-like integral membrane protein, 28-kDa
  • aquaporin-1
  • aquaporin 1, Colton blood group antigen
  • aquaporin-CHIP
  • urine water channel
  • water channel protein for red blood cells and kidney proximal tubule
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    English
    Aquaporin 1
    mammalian protein found in Homo sapiens
    • AQP1
    • aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group)
    • channel-like integral membrane protein, 28-kDa
    • aquaporin-1
    • aquaporin 1, Colton blood group antigen
    • aquaporin-CHIP
    • urine water channel
    • water channel protein for red blood cells and kidney proximal tubule

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    7 references
    retrieved
    8 April 2019
    stated in
    AQP1 is not only a water channel: it contributes to cell migration through Lin7/beta-catenin
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Towards a proteome-scale map of the human protein–protein interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Widespread macromolecular interaction perturbations in human genetic disorders
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    An empirical framework for binary interactome mapping
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Shifted Transversal Design smart-pooling for high coverage interactome mapping
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IPI
    water transmembrane transporter activity
    determination method or standard
    IDA
    IEA
    10 references
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IEA
    retrieved
    17 October 2017
    stated in
    Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Functional analysis of aquaporin-1 deficient red cells. The Colton-null phenotype
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Transmembrane water influx via aquaporin-1 is inhibited by barbiturates and propofol in red blood cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Glycerol permeability of mutant aquaporin 1 and other AQP-MIP proteins: inhibition studies
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    water channel activity
    determination method or standard
    EXP
    IDA
    IEA
    IMP
    27 references
    retrieved
    17 October 2017
    stated in
    MEK/ERK pathway mediates UVB-induced AQP1 downregulation and water permeability impairment in human retinal pigment epithelial cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IMP
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IEA
    retrieved
    17 October 2017
    stated in
    Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Functional characterization and localization of AQP3 in the human colon
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Aquaporin-1, nothing but a water channel.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Functional impairment of lens aquaporin in two families with dominantly inherited cataracts
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Novel variants in human Aquaporin-4 reduce cellular water permeability
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Mechanism of selectivity in aquaporins and aquaglyceroporins.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Water permeability and characterization of aquaporin-11.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Molecular Cloning and Expression of a Novel Human Aquaporin from Adipose Tissue with Glycerol Permeability
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Mercury-Sensitive Residues and Pore Site in AQP3 Water Channel
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    The subcellular localization of an aquaporin-2 tetramer depends on the stoichiometry of phosphorylated and nonphosphorylated monomers
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Structural determinants of water permeation through aquaporin-1
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Functional and molecular characterization of the human neutral solute channel aquaporin-9.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Identification of arylsulfonamides as Aquaporin 4 inhibitors
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Purification and functional characterization of aquaporin-8.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Functional characterization of a human aquaporin 0 mutation that leads to a congenital dominant lens cataract
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    water transmembrane transporter activity
    determination method or standard
    IDA
    9 references
    retrieved
    8 April 2019
    stated in
    Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Functional analysis of aquaporin-1 deficient red cells. The Colton-null phenotype
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Transmembrane water influx via aquaporin-1 is inhibited by barbiturates and propofol in red blood cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Glycerol permeability of mutant aquaporin 1 and other AQP-MIP proteins: inhibition studies
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    water channel activity
    determination method or standard
    EXP
    IBA
    IDA
    IMP
    8 references
    retrieved
    8 April 2019
    stated in
    MEK/ERK pathway mediates UVB-induced AQP1 downregulation and water permeability impairment in human retinal pigment epithelial cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IBA
    retrieved
    8 April 2019
    stated in
    Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Mechanism of selectivity in aquaporins and aquaglyceroporins.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Aquaporin-1, nothing but a water channel.
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Structural determinants of water permeation through aquaporin-1
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    EXP
    cell component
    apical plasma membrane
    determination method or standard
    IDA
    7 references
    retrieved
    8 April 2019
    stated in
    Long-range nonanomalous diffusion of quantum dot-labeled aquaporin-1 water channels in the cell plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 water channel expression in human kidney
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 in the choroid plexuses of developing mammalian brain
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Carbon dioxide transport through membranes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    plasma membrane
    determination method or standard
    IDA
    TAS
    14 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Evidence for a glycerol pathway through aquaporin 1 (CHIP28) channels
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Expression of aquaporin 1 and aquaporin 3 in fetal membranes and placenta in human term pregnancies with oligohydramnios
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    AQP1 is not only a water channel: it contributes to cell migration through Lin7/beta-catenin
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    AQP1 and AQP3, Psoriasin, and Nitric Oxide Synthases 1–3 are Inflammatory Mediators in Erythema Toxicum Neonatorum
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Changes in skeletal muscle expression of AQP1 and AQP4 in dystrophinopathy and dysferlinopathy patients
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Evidence for the presence of a Hg-inhibitable water-permeability pathway and aquaporin 1 in A5 salivary epithelial cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Induction of human aquaporin-1 gene by retinoic acid in human erythroleukemia HEL cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Localization and expression of the aquaporin-1 water channel in mesangial cells in the human glomerulus
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Human Protein Atlas
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    basolateral plasma membrane
    determination method or standard
    IDA
    7 references
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 water channel expression in human kidney
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 in the choroid plexuses of developing mammalian brain
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Carbon dioxide transport through membranes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Fetal development of membrane water channel proteins aquaporin-1 and aquaporin-4 in the human brain
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    biological process
    cellular response to mercury ion
    determination method or standard
    IDA
    5 references
    retrieved
    8 April 2019
    stated in
    Evidence for a glycerol pathway through aquaporin 1 (CHIP28) channels
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Psychiatric morbidity among adults living in private households, 2000
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Transmembrane water influx via aquaporin-1 is inhibited by barbiturates and propofol in red blood cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Glycerol permeability of mutant aquaporin 1 and other AQP-MIP proteins: inhibition studies
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    water transport
    determination method or standard
    IDA
    IEA
    IMP
    TAS
    11 references
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    TAS
    retrieved
    17 October 2017
    stated in
    MEK/ERK pathway mediates UVB-induced AQP1 downregulation and water permeability impairment in human retinal pigment epithelial cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IMP
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IEA
    retrieved
    17 October 2017
    stated in
    Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Functional analysis of aquaporin-1 deficient red cells. The Colton-null phenotype
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Transmembrane water influx via aquaporin-1 is inhibited by barbiturates and propofol in red blood cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Glycerol permeability of mutant aquaporin 1 and other AQP-MIP proteins: inhibition studies
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P29972&geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    water transport
    determination method or standard
    IDA
    IMP
    TAS
    10 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    MEK/ERK pathway mediates UVB-induced AQP1 downregulation and water permeability impairment in human retinal pigment epithelial cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Functional analysis of aquaporin-1 deficient red cells. The Colton-null phenotype
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Transmembrane water influx via aquaporin-1 is inhibited by barbiturates and propofol in red blood cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Glycerol permeability of mutant aquaporin 1 and other AQP-MIP proteins: inhibition studies
    GOA
    curator
    UniProt
    UniProt protein ID
    P29972
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29972
    determination method or standard
    IDA
    Gene Atlas image
    PBB GE AQP1 209047 at fs.png
    732 × 530; 11 KB
    0 references

    Identifiers

    UNII
    36141CLK2Y
    0 references
     
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                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q2083074&oldid=2022903739"