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Fas cell surface death receptor (Q1649375)

From Wikidata
mammalian protein found in Homo sapiens
  • Fas (TNF receptor superfamily, member 6)
  • FAS
  • FASLG receptor
  • TNF receptor superfamily member 6
  • APO-1 cell surface antigen
  • apoptosis antigen 1
  • CD95 antigen
  • tumor necrosis factor receptor superfamily, member 6
  • Fas AMA
  • Apo-1 antigen
  • apoptosis-mediating surface antigen FAS
  • apoptosis signaling receptor FAS
  • mutant tumor necrosis receptor superfamily member 6
  • tumor necrosis factor receptor superfamily member 6
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    English
    Fas cell surface death receptor
    mammalian protein found in Homo sapiens
    • Fas (TNF receptor superfamily, member 6)
    • FAS
    • FASLG receptor
    • TNF receptor superfamily member 6
    • APO-1 cell surface antigen
    • apoptosis antigen 1
    • CD95 antigen
    • tumor necrosis factor receptor superfamily, member 6
    • Fas AMA
    • Apo-1 antigen
    • apoptosis-mediating surface antigen FAS
    • apoptosis signaling receptor FAS
    • mutant tumor necrosis receptor superfamily member 6
    • tumor necrosis factor receptor superfamily member 6

    Statements

    image
    Fas receptor.png
    3,200 × 2,400; 1.84 MB
    0 references
    molecular function
    protein binding
    determination method or standard
    IPI
    18 references
    retrieved
    8 April 2019
    stated in
    Whole-exome-sequencing-based discovery of human FADD deficiency
    GOA
    curator
    UniProt
    UniProt protein ID
    P25445
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway
    GOA
    curator
    UniProt
    UniProt protein ID
    P25445
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Caveolin-1 mediates Fas–BID signaling in hyperoxia-induced apoptosis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Apoptosis-linked gene 2 binds to the death domain of Fas and dissociates from Fas during Fas-mediated apoptosis in Jurkat cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Inhibition of Daxx-mediated apoptosis by heat shock protein 27
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Yes and PI3K bind CD95 to signal invasion of glioblastoma
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The role of receptor internalization in CD95 signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25445
    determination method or standard
    IPI
    cell component
    biological process
    Gene Atlas image
    PBB GE FAS 204780 s at fs.png
    732 × 530; 11 KB
    0 references

    Identifiers

     
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