fangchinoline (Q15410976)

Fangchinoline (English)

14 October 2016

canonical SMILES

CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC

1 reference

Fangchinoline (English)

14 October 2016

isomeric SMILES

CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC

1 reference

Fangchinoline (English)

14 October 2016

found in taxon

Stephania hernandifolia

3 references

Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells

Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang and Stephania tetrandra S. Moore extracts

Alkaloids ofStephania hernandifolia

Stephania japonica

2 references

Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells

Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang and Stephania tetrandra S. Moore extracts

Stephania tetrandra

10 references

Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells

Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang and Stephania tetrandra S. Moore extracts

A New Monoquaternqry Bisbenzylisoquinoline Alkakoid from Stephania testrandra

Four New Bisbenzylisoquinoline Alkaloids from the Root of Stephania Tetrandra (Fen-Fang Ji)

Analysis of tetrandrine and fangchinoline in traditional Chinese medicines by capillary electrophoresis

Fangchinoline inhibited the antinociceptive effect of morphine in mice

Protective effect of fangchinoline on cyanide-induced neurotoxicity in cultured rat cerebellar granule cells

Separation of Alkaloids Extracted from Stephania Tetranda S. Moore by Analytical High-Speed Countercurrent Chromatography

Studies on Inhibitory Activity against Acetylcholinesterase of New Bisbenzylisoquinoline Alkaloid and Its Related Compounds

Fangchinoline Induced G1/S Arrest by Modulating Expression of p27, PCNA, and Cyclin D in Human Prostate Carcinoma Cancer PC3 Cells and Tumor Xenograft

Cyclea barbata

1 reference

Alkaloids from menispermaceae drugs from Thailand. IV. Isolation and structure of two berbamine alkaloids (author's transl)

Cyclea peltata

1 reference

New alkaloids and related artifacts from Cyclea peltata

Isopyrum thalictroides

2 references

Alkaloids from Isopyrum thalictroides

Complement-mediated antiinflammatory effect of bisbenzylisoquinoline alkaloid fangchinoline

Pachygone dasycarpa

1 reference

(+)-Angchibangkine, a new type of bisbenzylisoquinoline alkaloid, and other dimers from Pachygone dasycarpa

Thalictrum orientale

1 reference

Alkaloids of thalictrum orientale growing in Turkey

Strychnopsis thouarsii

2 references

In VitroAntimalarial Activity and Chloroquine Potentiating Action of Two Bisbenzylisoquinoline Enantiomer Alkaloids Isolated fromStrychnopsis thouarsii and Spirospermum penduliflorum

Isoquinoline alkaloid constituents of Spirospermum penduliflorum and Strychnopsis thouarsii (Menispermaceae)

Stephania rotunda

1 reference

Antiplasmodial activity of three bisbenzylisoquinoline alkaloids from the tuber of Stephania rotunda

mass

608.289±0 dalton

1 reference

Fangchinoline (English)

InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29-/m0/s1

14 October 2016

Identifiers

InChI

1 reference

Fangchinoline (English)

14 October 2016

2 references

Fangchinoline (English)

14 October 2016

ChEBI release 2020-09-01

CAS Registry Number

436-77-1

2 references

Global Substance Registration System

UNII

953592C3ZB

fangchinoline (English)

14 October 2016

https://commonchemistry.cas.org/detail?cas_rn=436-77-1

9 April 2021

1 reference

(1beta)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol (English)

14 October 2016

2 references

Fangchinoline (English)

14 October 2016

ChEBI ID

132893

mapping relation type

exact match

2 references

ChEBI release 2019-10-02

International Chemical Identifier

InChI

InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29-/m0/s1

1 reference

FANGCHINOLINE (English)

14 October 2016

2 references

inferred from InChIKey

1 reference

1 reference

DSSTOX compound identifier

0 references

0 references

2 references

Global Substance Registration System

UNII

953592C3ZB

fangchinoline (English)

14 October 2016