Myosin VA (Q15320975)

Myosin S1 fragment, N-terminal

1 reference

kinesin motor domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Dilute domain, protein family

1 reference

Class V myosin, motor domain, protein family

1 reference

Myosin 5a, cargo-binding domain, protein family

1 reference

Myosin, N-terminal, SH3-like, protein family

1 reference

Myosin head, motor domain, protein family

1 reference

IQ motif, EF-hand binding site, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

calmodulin binding

5 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

14 February 2019

Myosin V exhibits a high duty cycle and large unitary displacement

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin V: regulation by calcium, calmodulin, and the tail domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

The high molecular weight neurofilament subunit plays an essential role in axonal outgrowth and stabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

protein binding

5 references

9 August 2016

14 February 2019

Molecular cloning and characterization of neural activity-related RING finger protein (NARF): a new member of the RBCC family is a candidate for the partner of myosin V

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Missense mutations in the globular tail of myosin-Va in dilute mice partially impair binding of Slac2-a/melanophilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Rab27a regulates the peripheral distribution of melanosomes in melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

actin binding

5 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

14 February 2019

Myosin V exhibits a high duty cycle and large unitary displacement

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

The structural basis of myosin V processive movement as revealed by electron cryomicroscopy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

microfilament motor activity

1 reference

9 August 2016

ATP binding

1 reference

9 August 2016

cytoskeletal motor activity

1 reference

9 August 2016

microfilament motor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin V exhibits a high duty cycle and large unitary displacement

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin V: regulation by calcium, calmodulin, and the tail domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

SNARE binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

cytoskeletal motor activity

3 references

syntaxin-1 binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

ATP-dependent protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

protein heterodimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

protein dimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

calcium-dependent protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

actin filament binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

1 reference

14 February 2019

disordered domain specific binding

1 reference

14 February 2019

Identification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilin

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

cell component

cytoplasm

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

cytosol

1 reference

14 February 2019

The acroplaxome is the docking site of Golgi-derived myosin Va/Rab27a/b- containing proacrosomal vesicles in wild-type and Hrb mutant mouse spermatids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

melanosome

3 references

16 September 2017

The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99104&geneProductId=UniProtKB:Q99104

16 September 2017

Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99104&geneProductId=UniProtKB:Q99104

16 September 2017

Identification of an organelle receptor for myosin-Va

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99104&geneProductId=UniProtKB:Q99104

insulin-responsive compartment

1 reference

14 February 2019

Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

photoreceptor outer segment

1 reference

14 February 2019

The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

microtubule plus-end

1 reference

14 February 2019

Melanophilin and myosin Va track the microtubule plus end on EB1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

intermediate filament

1 reference

14 February 2019

Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

actomyosin

1 reference

14 February 2019

Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

myosin complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

14 February 2019

Myosin V exhibits a high duty cycle and large unitary displacement

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

secretory granule

1 reference

16 September 2017

Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99104&geneProductId=UniProtKB:Q99104

soma

1 reference

16 September 2017

Novel myosin heavy chain encoded by murine dilute coat colour locus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99104&geneProductId=UniProtKB:Q99104

unconventional myosin complex

1 reference

14 February 2019

Identification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilin

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

synaptic vesicle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

axon

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

dendrite

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

melanosome

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Identification of an organelle receptor for myosin-Va

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

actomyosin, myosin complex part

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

neuron projection

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

Schaffer collateral - CA1 synapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

postsynaptic actin cytoskeleton

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

glutamatergic synapse

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

ribonucleoprotein complex

EXP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

biological process

melanosome localization

4 references

9 August 2016

14 February 2019

Missense mutations in the globular tail of myosin-Va in dilute mice partially impair binding of Slac2-a/melanophilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Rab27a regulates the peripheral distribution of melanosomes in melanocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

endoplasmic reticulum localization

3 references

9 August 2016

14 February 2019

The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

The dilute-lethal (dl) gene attacks a Ca2+ store in the dendritic spine of Purkinje cells in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

melanosome transport

5 references

9 August 2016

14 February 2019

Effects of genic substitution at the agouti, brown, albino, dilute, and pink-eyed dilution loci on the proliferation and differentiation of mouse epidermal melanocytes in serum-free culture

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

transport

1 reference

9 August 2016

vesicle transport along actin filament

4 references

9 August 2016

14 February 2019

Myosin V exhibits a high duty cycle and large unitary displacement

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

Ensembl genome database project

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

protein transport

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

pigmentation

1 reference

9 August 2016

melanocyte differentiation

4 references

9 August 2016

14 February 2019

Novel myosin heavy chain encoded by murine dilute coat colour locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

The murine dilute suppressor gene encodes a cell autonomous suppressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

locomotion involved in locomotory behavior

3 references

9 August 2016

14 February 2019

The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Abnormal expression of tyrosine hydroxylase immunoreactivity in Purkinje cells precedes the onset of ataxia in dilute-lethal mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

membrane organization

1 reference

9 August 2016

actin filament-based movement

1 reference

9 August 2016

secretory granule localization

1 reference

9 August 2016

regulation of exocytosis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

pigmentation

Identification of a novel myosin-Va mutation in an ataxic mutant rat, dilute-opisthotonus

14 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Head Region Mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

The Effects of Genotype and Cell Environment on Melanoblast Differentiation in the House Mouse.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Dilute-Coat-Color Locus of Mice: Nucleotide Sequence Analysis of the d+2J and d+Ha Revertant Alleles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Somatic and germ-line reverse mutation rates of the retrovirus-induced dilute coat-color mutation of DBA mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Dilute suppressor dsu acts semidominantly to suppress the coat color phenotype of a deletion mutation, dl20J, of the murine dilute locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Tail Region Mutations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

The murine dilute suppressor gene encodes a cell autonomous suppressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Excision of the DBA ecotropic provirus in dilute coat-color revertants of mice occurs by homologous recombination involving the viral LTRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Effect of genic substitution on the incorporation of tyrosine into the melanin of mouse skin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

hair follicle maturation

1 reference

14 February 2019

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

establishment of endoplasmic reticulum localization to postsynapse

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

regulation of postsynaptic cytosolic calcium ion concentration

EXP

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

14 February 2019

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

axo-dendritic protein transport

EXP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

positive regulation of cellular response to insulin stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

positive regulation of protein localization to plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

positive regulation of vascular associated smooth muscle cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99104

IQ motif, EF-hand binding site

has part(s)

1 reference

Myosin head, motor domain

1 reference

Dilute domain

1 reference

Class V myosin, motor domain

1 reference

Myosin, N-terminal, SH3-like

1 reference

Myosin 5a, cargo-binding domain

1 reference

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016