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SREBF chaperone (Q14913792)

From Wikidata

mammalian protein found in Mus musculus

Scap
sterol regulatory element-binding protein cleavage-activating protein
Sreb cleavage-activating protein
uniprot:Q6GQT6
SREBP cleavage activating protein

Language	Label	Description	Also known as
default for all languages	No label defined
English	SREBF chaperone	mammalian protein found in Mus musculus	Scap sterol regulatory element-binding protein cleavage-activating protein Sreb cleavage-activating protein uniprot:Q6GQT6 SREBP cleavage activating protein

Statements

1 reference

25 May 2022

UniProt protein ID

WD40/YVTN repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

WD40-repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

Sterol regulatory element-binding protein cleavage-activating protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Sterol-sensing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

cholesterol binding

determination method or standard

1 reference

14 February 2019

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

Golgi apparatus

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

ER to Golgi transport vesicle membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

integral component of membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

cytoplasmic vesicle

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

endoplasmic reticulum membrane

determination method or standard

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

14 February 2019

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

biological process

lipid metabolism

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

regulation of fatty acid biosynthetic process

determination method or standard

1 reference

14 February 2019

Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

regulation of cholesterol biosynthetic process

determination method or standard

1 reference

14 February 2019

Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

response to hypoxia

determination method or standard

1 reference

14 February 2019

Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

steroid metabolic process

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

regulation of fatty acid metabolic process

determination method or standard

1 reference

14 February 2019

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

response to insulin

determination method or standard

1 reference

14 February 2019

Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

determination method or standard

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

SREBP signaling pathway

determination method or standard

immune response

determination method or standard

1 reference

14 February 2019

Aging of myelinating glial cells predominantly affects lipid metabolism and immune response pathways

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

cellular lipid metabolic process

determination method or standard

1 reference

14 February 2019

Aging of myelinating glial cells predominantly affects lipid metabolism and immune response pathways

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

Sterol-sensing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

WD40 repeat, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000095953

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000095953

ENSMUSP00000142458

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142458

ENSMUSP00000142919

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142919

ENSMUSP00000143369

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143369

ENSMUSP00000143710

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143710

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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