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RAD51 recombinase (Q14907735)

From Wikidata
mammalian protein found in Mus musculus
  • RAD51 homolog A
  • DNA repair protein RAD51 homolog 1
  • Rad51
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    English
    RAD51 recombinase
    mammalian protein found in Mus musculus
    • RAD51 homolog A
    • DNA repair protein RAD51 homolog 1
    • Rad51

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    5 references
    retrieved
    14 February 2019
    stated in
    Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination
    GOA
    curator
    UniProt
    UniProt protein ID
    Q08297
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IPI
    retrieved
    14 February 2019
    stated in
    Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IPI
    cell component
    condensed nuclear chromosome
    determination method or standard
    IDA
    9 references
    retrieved
    27 March 2018
    stated in
    Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Meiosis in mice without a synaptonemal complex
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    27 March 2018
    stated in
    Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08297&geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    condensed chromosome
    determination method or standard
    IDA
    5 references
    retrieved
    14 February 2019
    stated in
    Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Meiotic arrest and aneuploidy in MLH3-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase III beta
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    nucleus
    determination method or standard
    IDA
    ISS
    IEA
    ISO
    8 references
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q08297
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    ISS
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    ISO
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q08297
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IEA
    retrieved
    14 February 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IEA
    retrieved
    14 February 2019
    stated in
    Rad51 expression and localization in B cells carrying out class switch recombination
    GOA
    curator
    UniProt
    UniProt protein ID
    Q08297
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    RAD51 mutants cause replication defects and chromosomal instability
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Disruption of Chtf18 Causes Defective Meiotic Recombination in Male Mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    condensed nuclear chromosome
    determination method or standard
    IBA
    IDA
    10 references
    retrieved
    14 February 2019
    stated in
    FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Meiosis in mice without a synaptonemal complex
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IDA
    retrieved
    14 February 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08297
    determination method or standard
    IBA
    biological process

    Identifiers

     
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