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Interleukin 6 (Q14865240)

From Wikidata
mammalian protein found in Mus musculus
  • B-cell hybridoma growth factor
  • Il6
  • interleukin HP-1
  • interleukin-6
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    English
    Interleukin 6
    mammalian protein found in Mus musculus
    • B-cell hybridoma growth factor
    • Il6
    • interleukin HP-1
    • interleukin-6

    Statements

    molecular function
    cytokine activity
    determination method or standard
    IDA
    IEA
    ISO
    8 references
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    ISO
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P08505
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Induction of endogenous retroviral gene product (SU) as an acute-phase protein by IL-6 in murine hepatocytes
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    cell component
    extracellular space
    determination method or standard
    IDA
    IEA
    ISO
    25 references
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    ISO
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P08505
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IEA
    retrieved
    9 May 2019
    stated in
    Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Endocrine regulation of energy metabolism by the skeleton
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    An Extraribosomal Function of Ribosomal Protein L13a in Macrophages Resolves Inflammation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Fc epsilon RI gamma-ITAM is differentially required for mast cell function in vivo
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Altered cytokine production in mice lacking P2X(7) receptors
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Accessory protein-like is essential for IL-18-mediated signaling
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Negative regulation of Toll-like-receptor signaling by IRF-4.
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Interleukin-1, interleukin-6, and tumor necrosis factor alpha are produced in the mouse uterus during the estrous cycle and are induced by estrogen and progesterone
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Critical role of NOD2 in regulating the immune response to Staphylococcus aureus
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    retrieved
    9 May 2019
    stated in
    Adenosine receptors in regulation of dendritic cell differentiation and function
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08505
    determination method or standard
    IDA
    biological process

    Identifiers

     
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